Developing asthma in childhood from exposure to secondhand tobacco smoke
Insights from a meta-regression
Bibliographic Data
| ID | 19475255 |
|---|---|
| Authors | Kathleen Vork (California Environmental Protection Agency), Kathleen L Vork (California Environmental Protection Agency), Rachel Broadwin (0000-0002-3572-8929, California Environmental Protection Agency), Robert Blaisdell (California Environmental Protection Agency), Robert J Blaisdell (California Environmental Protection Agency) |
| Year | 2008 |
| Volume | 13 |
| Issue | 4 |
| Pages | 1313-1325 |
| Publication date | 2008-08-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Ciência & Saúde Coletiva (JOURNAL) |
| Journal identifiers | ISSN: 1413-8123 • E-ISSN: 1678-4561 |
| Publisher | FapUNIFESP (SciELO) (PUBLISHER) |
| DOI | 10.1590/s1413-81232008000400028 |
| PMID | 17938726 |
| PMCID | PMC2022647 |
| OpenAlex | W2097336551 |
| SCIELO_PID | S1413-81232008000400028 |
| Language | EN |
| Citations received | 6 |
| References cited | 51 |
Studies have shown links between household secondhand tobacco smoke (SHS) exposure and induction of childhood asthma. But the true nature of this link remains unclear in many studies. We conducted a meta-analysis of studies published from 1970 to 2005 to uncover consistent patterns of relative risk estimates (RRs), and found substantial heterogeneity within initial summary RRs of 1.48 [95% confidence interval (CI), 1.32-1.65], 1.25 (1.21-1.30), and 1.21 (1.08-1.36), for ever, current, and incident asthma, respectively. Lack of control for type of atopy history (familial or child) and child's own smoking status within studies and age category altered summary RRs in separate metaregressions. After adjustments, consistent patterns of association emerged between SHS exposure and childhood asthma induction. Our summary RR of 1.33 (95% CI, 1.14-1.56) from studies of incident asthma among older children (618 years old) is 1.27 times the estimate from studies of younger children and higher than estimates from earlier meta-analyses. This showns that exposure duration may be a more important factor than previously understood, and suggests that SHS could be a more fundamental cause of childhood asthma than some previous meta-analyses have indicated
Asthma · Atopy · Confidence interval · Environmental health · Meta-analysis · Passive smoking · Pathology · Public health · Relative risk · Secondhand smoke · Tobacco control · Tobacco smoke · Air Quality and Health Impacts · Asthma and respiratory diseases · Demography · Medicine · Smoking Behavior and Cessation · Immunology · Internal Medicine · Pediatrics
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| Unique citing works | 6 |
|---|---|
| Citations per year | 0,35 |
| Citation span | 2009 - 2014 (6) |
| Citation velocity | historical |
| Highly cited | No |