Human biorhythms and their monitoring using biological fluid indicators

Most physiological processes in the human body are governed by genetically determined biorhythms, which are key factors of natural selection and adaptation. Circadian rhythms regulate not only daily biological processes but also their underlying molecular basis. This knowledge may be useful for developing therapeutic strategies for a range of diseases. Particular importance is attributed to research in biological rhythms for professions involving shift work and night work, as it allows identifying periods of increased vulnerability of the human body. Changes in living, working, and rest conditions may lead to disturbances and disruptions of biological rhythms: the internal biological clock may accelerate or decelerate, resulting in desynchronization, deterioration of well-being, and the development of chronopathological conditions, including an increased risk of cardiovascular and endocrine disorders, psychoemotional disturbances, and reduced work capacity. Therefore, chronomedicine addresses the application of knowledge about biorhythm patterns for the prevention, diagnosis, and treatment of human diseases. Monitoring of human biorhythms can be performed using various biological fluids (blood, urine, saliva), depending on the research objectives and laboratory capabilities

Biological clock · Biological effect · Biological materials · Biological organism · Chronobiology · Circadian rhythm · Organism · Circadian rhythm and melatonin · Sleep and Work-Related Fatigue · Thermoregulation and physiological responses

• Chronophysiological Features of the Normal Electrolyte Composition of Human Saliva

  Open Access•L V Bel''Skaya, Lyudmila V Bel''Skaya et al.•Ekologiya Cheloveka (Human Ecology•2018

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