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Effect of psilocybin-assisted psychotherapy on anxiety symptoms

A systematic review and meta-analysis

Bibliographic Data

ID19489751
AuthorsAlex Hood (0009-0007-9378-4455, Baylor University), Gary Elkins (0000-0002-9546-0020, Baylor University)
Year2026
Publication date2026-05-29
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Psychedelic Studies (JOURNAL)
Journal identifiersISSN: 2559-9283 • E-ISSN: 2559-9283
PublisherAkademiai Kiado Zrt. (PUBLISHER • HU)
DOI10.1556/2054.2026.00507
OpenAlexW7162785692
LanguageEN
References cited84

Anxiety · Clinical trial · Demographics · Psychological intervention · Randomized controlled trial · Systematic review · Forensic Toxicology and Drug Analysis · Pain Management and Placebo Effect · Psychedelics and Drug Studies

  • Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer

    Open Access•Roland R Griffiths, Matthew W Johnson et al.•Journal of Psychopharmacology•2016

  • Psilocybin with psychological support for treatment-resistant depression

    Open Access•Robin Carhart‐Harris, R L Carhart-Harris et al.•Psychopharmacology•2018

  • Improving the content validity of the mixed methods appraisal tool

    Open Access•Quan Nha Hong, Pierre Pluye et al.•Journal of Clinical Epidemiology•2019

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  • Pilot Study of Psilocybin Treatment for Anxiety in Patients With Advanced-Stage Cancer

    Charles S Grob, Alicia Danforth et al.•Archives of General Psychiatry•2011

  • The PRISMA 2020 statement

    Open Access•Matthew J Page, Joanne E McKenzie et al.•Journal of Clinical Epidemiology•2021

  • Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder

    Open Access•A K Davis, Frederick S Barrett et al.•JAMA Psychiatry•2021

  • Meta-analysis in clinical trials

    Open Access•Rebecca DerSimonian, Nan M Laird et al.•Controlled Clinical Trials•1986

  • Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer

    Open Access•Stephen Ro, Stephen Ross et al.•Journal of Psychopharmacology•2016

  • Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression

    Open Access•Guy M Goodwin, Scott T Aaronson et al.•New England Journal of Medicine•2022

  • Sensitivity to change and minimal clinically important difference of the 7-item Generalized Anxiety Disorder Questionnaire (GAD-7)

    Open Access•Anne Toussaint, Paul Hüsing et al.•Journal of Affective Disorders•2020

  • The validity of the Hospital Anxiety and Depression Scale

    Open Access•Ingerid Bjelland, Ingvar Bjelland et al.•Journal of Psychosomatic Research•2002

  • Trial of Psilocybin versus Escitalopram for Depression

    Open Access•Robin Carhart-Harris, Robin Carhart‐Harris et al.•New England Journal of Medicine•2021

  • A Brief Measure for Assessing Generalized Anxiety Disorder

    Robert L Spitzer, Carmen Pérez de los Ríos et al.•A.M.A. Archives of Internal…•2006

  • The Mixed Methods Appraisal Tool (MMAT) version 2018 for information professionals and researchers

    Quan Nha Hong, Sergi Fàbregue et al.•Education for Information•2018

  • A systematic review and meta-analysis of transdiagnostic cognitive behavioural therapies for emotional disorders

    Open Access•Carmen Schaeuffele, Laura E Meine et al.•Nature Human Behaviour•2024

  • Serotoninergic antidepressants combination in psilocybin-assisted psychotherapy

    Open Access•André Do, Vanessa Michaud et al.•Frontiers in Psychiatry•2024

  • Nature-themed video intervention may improve cardiovascular safety of psilocybin-assisted therapy for alcohol use disorder

    Open Access•Keith G Heinzerling, Karina Sergi et al.•Frontiers in Psychiatry•2023

  • Psilocybin-assisted psychotherapy for methamphetamine dependence

    Open Access•Jeanne Brett, Jonathan Brett et al.•Frontiers in Psychiatry•2024

Citation velocityhistorical
Highly citedNo

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