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The Development and Acceptability of a Psychology‐Based Intervention for Debilitating Symptom Complexes Attributed to Ticks

Bibliographic Data

ID19506260
AuthorsAnita L Dharan (0000-0002-3968-656X, Austin Health), Valerie M Z Yap (Department of Psychiatry University of Melbourne, Austin Health Heidelberg Victoria Australia), Valerie Yap (0000-0002-7425-3647, Austin Health), Richard Kanaan (0000-0003-0992-1917, Austin Health, corresponding author), Richard A Kanaan (Department of Psychiatry University of Melbourne, Austin Health Heidelberg Victoria Australia), Georgina Oliver (0000-0002-9215-2225, Austin Health), Yen D Y Sim (Austin Health), Sabine Braat (0000-0003-1997-3999, The University of Melbourne), Georgia Cotter (Austin Health), Mary Lou Chatterton (0000-0003-4902-9448, Monash Health), Cathrine Mihalopoulos (0000-0002-7127-9462, Monash Health), Sarah J Wilson (0000-0002-2678-1576, The University of Melbourne), Trudie Chalder (0000-0003-0775-1045, King's College London)
Year2026
Volume29
Issue2
Pagese70634-e70634
Publication date2026-04-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueHealth Expectations (JOURNAL)
Journal identifiersISSN: 1369-6513 • E-ISSN: 1369-7625
PublisherWiley (PUBLISHER • GB)
DOI10.1111/hex.70634
PMID41821246
OpenAlexW7135223188
LanguageEN
References cited39

BACKGROUND: Debilitating Symptom Complexes Attributed to Ticks (DSCATT) is a chronic, debilitating illness associated with tick bites in Australia. DSCATT is of unknown aetiology, can impact emotional well-being and has no recognised treatments. OBJECTIVE: The development and piloting of a novel psychotherapeutic adjunctive intervention for DSCATT that aimed to increase daily functioning, improve quality of life and reduce the impact of symptoms in people with DSCATT. METHODS: This is a single-site, intervention development and acceptability study. The intervention was developed iteratively according to a Human-Centred Design (HCD) approach and manualised across four phases, with input from end users at each phase: qualitative interviews, development of the intervention, piloting, and revising and refining the intervention. Acceptability of the prototype intervention was evaluated through thematic template analysis of exit interviews. Self-report measures were completed before and after intervention delivery. RESULTS: Following qualitative interviews with 13 participants (11 females and 2 males; aged 35-70 years), the intervention was informed by an Acceptance and Commitment Therapy (ACT) model interwoven with cognitive and behavioural strategies that targeted DSCATT-specific difficulties. The manualised intervention consisted of 12 1-h weekly individual sessions, delivered by psychologists via Telehealth (video call or telephone). Modules addressed the six core psychological processes of ACT, alongside DSCATT-specific modules addressing cognitive function, sleep and social relationships. Pilot testing and follow-up interviews were conducted in a separate sample of six individuals with DSCATT (all females; aged 46-71 years). All participants reported that the approach benefited their emotional well-being and overall health and would recommend it to others with DSCATT. CONCLUSIONS: This is a novel and theoretically driven psychotherapeutic intervention for DSCATT, co-produced with patient involvement across four phases. Pilot testing suggested the manualised intervention was feasible and acceptable, supporting future evaluation of feasibility and treatment outcomes with randomised controlled trials. PATIENT OR PUBLIC CONTRIBUTION: This study involved the engagement and participation of individuals with DSCATT across four stages of the project, according to an HCD approach-the choice of the intervention; the development of the intervention; the piloting of the intervention, and the assessment of the intervention. TRIAL REGISTRATION: The pilot study component of this project was prospectively registered on the Australian and New Zealand Clinical Trial Registry (ANZCTR); trial ID: ACTRN12621001032842

Clinical trial · Component (thermodynamics) · Intervention (counseling) · MEDLINE · Pilot trial · Randomized controlled trial · Obsessive-Compulsive Spectrum Disorders · Personality Disorders and Psychopathology · Psychosomatic Disorders and Their Treatments

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Highly citedNo
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