Frequency of and reasons for medication non-fulfillment and non-persistence among American adults with chronic disease in 2008
Reasons for medication non-fulfillment and non-persistence
Bibliographic Data
| ID | 19507555 |
|---|---|
| Authors | Colleen A Mchorney (0000-0002-5944-9158, Merck & Co., Inc., Rahway, NJ, USA (United States), corresponding author), C Victor Spain (0000-0002-5197-8776, Merck & Co., Inc., Rahway, NJ, USA (United States)) |
| Year | 2011 |
| Volume | 14 |
| Issue | 3 |
| Pages | 307-320 |
| Publication date | 2011-09-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Health Expectations (JOURNAL) |
| Journal identifiers | ISSN: 1369-6513 • E-ISSN: 1369-7625 |
| Publisher | Wiley (PUBLISHER • GB) |
| DOI | 10.1111/j.1369-7625.2010.00619.x |
| PMID | 20860775 |
| OpenAlex | W1607325117 |
| Language | EN |
| Citations received | 4 |
| References cited | 44 |
OBJECTIVE To identify self-reported reasons why adults with chronic disease do not fill a new prescription (medication non-fulfillment) and/or stop taking a medication without their physician telling them to do so (lack of medication persistence). METHODS Participants were sampled in 2008 from a national, internet-based panel of American adults with chronic disease. A total of 19 830 respondents answered questions about medication non-fulfillment and medication non-persistence and reasons for non-fulfillment and non-persistence. Among persons self-identified as non-fulfillers and non-persisters, statistical analyses assessed the association between reported reasons for non-fulfillment and non-persistence and chronic disease. A subsample of respondents completed an additional survey which included multi-item scales assessing matched constructs of most of the reasons for non-fulfillment and non-persistence. The convergent validity of the self-reported reasons was assessed against the multi-item scales. RESULTS The same four reasons were most commonly reported for both medication non-fulfillment and medication non-persistence: paying for the medication a financial hardship (56 and 43%, respectively); fear or experience of side effects (46 and 35%, respectively); generic concerns about medications (32 and 23%, respectively); and lack of perceived need for the medication (25 and 23%, respectively). The frequency with which the reasons were reported varied somewhat by chronic disease. The convergent validity of most of the self-reported reasons was confirmed against multi-item scales measuring matched constructs. CONCLUSIONS The same top reasons for medication non-fulfillment and non-adherence were observed in a large internet-based sample of American adults with chronic disease. Future efforts to improve medication adherence should address patients' medication concerns, perceived need for medications, and perceived medication affordability
Chronic disease · Disease · Family medicine · Health Systems, Economic Evaluations, Quality of Life · Medication Adherence and Compliance · Medicine · Pharmaceutical Practices and Patient Outcomes · Psychology · Gerontology · Internal Medicine
Social Risk Factors for Medication Nonadherence
Stakeholder point of view on prescription drug affordability - a systematic literature review and content analysis
Cost-related Nonadherence to Medication Treatment Plans
Social Determinants of Health, Cost-related Nonadherence, and Cost-reducing Behaviors Among Adults With Diabetes
| Citations per year | 0.4 |
|---|---|
| Citation span | 2016 - 2021 (6) |
| Highly cited | No |