Will the introduction of non‐invasive prenatal testing for D own's syndrome undermine informed choice
Bibliographic Data
| ID | 19508375 |
|---|---|
| Authors | Caroline Silcock (University College London Hospitals NHS Foundation Trust & UCL Institute for Women's Health London UK), Lih‐mei Liao (University College London Hospitals NHS Foundation Trust & UCL Institute for Women's Health London UK), Melissa Hill (0000-0003-3900-1425, UCL Institute of Child Health Great Ormond Street Hospital for Children NHS Trust, and Fetal Medicine Unit, University College London Hospitals NHS Foundation Trust London UK), Lyn S Chitty (0000-0002-4857-7138, UCL Institute of Child Health London UK) |
| Year | 2015 |
| Volume | 18 |
| Issue | 5 |
| Pages | 1658-1671 |
| Publication date | 2015-10-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Health Expectations (JOURNAL) |
| Journal identifiers | ISSN: 1369-6513 • E-ISSN: 1369-7625 |
| Publisher | Wiley (PUBLISHER • GB) |
| DOI | 10.1111/hex.12159 |
| PMID | 26039796 |
| OpenAlex | W2081940197 |
| Language | EN |
| Citations received | 5 |
| References cited | 41 |
OBJECTIVE: To investigate whether the introduction of non-invasive pre-natal testing for Down's syndrome (DS) has the potential to undermine informed choice. PARTICIPANTS: Three hundred and ninety-three health professionals; 523 pregnant women. METHODS: A cross-sectional questionnaire study across nine maternity units and three conferences in the UK designed to assess opinions regarding test delivery and how information should be communicated to women when offered Down's syndrome screening (DSS) or diagnosis using invasive (IDT) or non-invasive testing (NIPT). RESULTS: Both pregnant women and health professionals in the NIPT and DSS groups were less likely than the IDT group to consider that testing should take place at a return visit or that obtaining written consent was necessary, and more likely to think testing should be carried out routinely. Compared to health professionals, pregnant women expressed a stronger preference for testing to occur on the same day as pre-test counselling (P = 0.000) and for invasive testing to be offered routinely (P = 0.000). They were also more likely to indicate written consent as necessary for DSS (P = 0.000) and NIPT (P < 0.05). CONCLUSIONS: Health professionals and pregnant women view the consenting process differently across antenatal test types. These differences suggest that informed choice may be undermined with the introduction of NIPT for DS into clinical practice. To maintain high standards of care, effective professional training programmes and practice guidelines are needed which prioritize informed consent and take into account the views and needs of service users
Alternative medicine · Decision aids · Family medicine · Gynecology · Health care · Health professionals · Informed consent · Preference · Down syndrome and intellectual disability research · Ethics in Clinical Research · Medicine · Nursing · Prenatal Screening and Diagnostics · Psychology
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Ethnic differences in informed decision-making about prenatal screening for Down's syndrome
Too many choices? Hospital and community staff reflect on the future of prenatal screening
| Unique citing works | 5 |
|---|---|
| Citations per year | 0,45 |
| Citation span | 2015 - 2025 (11) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 5 |