Ethical Considerations in Determining Standard of Prevention Packages for HIV Prevention Trials
Examining P r EP
Bibliographic Data
| ID | 19516442 |
|---|---|
| Authors | Bridget Haire (0000-0002-0657-9610, The University of Sydney, corresponding author), Morenike O Folayan (0000-0002-9008-7730), Catherine Hankins (0000-0002-1642-8592, London School of Hygiene & Tropical Medicine), Jane Sugarman (0000-0001-7022-8332, Association of Academic Health Centers), Jeremy Sugarman, Sheena McCormack (0000-0002-7829-1325, Chelsea and Westminster Hospital), Gita Ramjee (South African Medical Research Council), Mitchell Warren (0000-0003-3626-7156) |
| Year | 2013 |
| Volume | 13 |
| Issue | 2 |
| Pages | 87-94 |
| Publication date | 2013-08-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Developing World Bioethics (JOURNAL) |
| Journal identifiers | ISSN: 1471-8731 • E-ISSN: 1471-8847 |
| Publisher | Wiley (PUBLISHER • GB) |
| DOI | 10.1111/dewb.12032 |
| PMID | 23725227 |
| PMCID | PMC3716830 |
| OpenAlex | W1958981243 |
| Language | EN |
| Citations received | 2 |
| References cited | 24 |
The successful demonstration that antiretroviral ( ARV ) drugs can be used in diverse ways to reduce HIV acquisition or transmission risks – either taken as pre‐exposure prophylaxis ( PrEP ) by those who are uninfected or as early treatment for prevention ( T4P ) by those living with HIV – expands the armamentarium of existing HIV prevention tools. These findings have implications for the design of future HIV prevention research trials. With the advent of multiple effective HIV prevention tools, discussions about the ethics and the feasibility of future HIV prevention trial designs have intensified. This article outlines arguments concerning the inclusion of newly established ARV ‐based HIV prevention interventions as standard of prevention in HIV prevention trials from multiple perspectives. Ultimately, there is a clear need to incorporate stakeholders in a robust discussion to determine the appropriate trial design for each study population
Ethics in Clinical Research · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Medicine · Immunology
Antiretroviral Prophylaxis for HIV Prevention in Heterosexual Men and Women
Male circumcision for HIV prevention in young men in Kisumu, Kenya
Randomized, Controlled Intervention Trial of Male Circumcision for Reduction of HIV Infection Risk
Antiretroviral Preexposure Prophylaxis for Heterosexual HIV Transmission in Botswana
Preexposure Prophylaxis for HIV Infection among African Women
Emtricitabine-Tenofovir Concentrations and Pre-Exposure Prophylaxis Efficacy in Men Who Have Sex with Men
Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women
Male circumcision for HIV prevention in men in Rakai, Uganda
Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men
Prevention of HIV-1 Infection with Early Antiretroviral Therapy
The benefits of participatory methodologies to develop effective community dialogue in the context of a microbicide trial feasibility study in Mwanza, Tanzania
Gradations of Researchers’ Obligation to Provide Ancillary Care for HIV/Aids in Developing Countries
| Citations per year | 0.25 |
|---|---|
| Citation span | 2018 - 2025 (8) |
| Highly cited | No |