Effect of central sensitization on dizziness-related symptoms of persistent postural-perceptual dizziness
Bibliographic Data
| ID | 19536770 |
|---|---|
| Authors | Kazuaki Hashimoto (0000-0003-3007-8717, Toho University, corresponding author), Takeaki Takeuchi (0000-0003-4399-2786, Toho University), Takayuki Ueno (0009-0003-6804-3947, Toho University), Shunsuke Suka (Toho University), Miki Hiiragi (Toho University), Maya Yamada (Toho University), Akiko Koyama (0000-0002-0680-4240, Toho University), Yuzo Nakamura (Toho University), Jun Miyakoda (Toho University), Masahiro Hashizume (0000-0003-4720-1750, Toho University) |
| Year | 2022 |
| Volume | 16 |
| Issue | 1 |
| Pages | 7-7 |
| Publication date | 2022-03-07 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | BioPsychoSocial Medicine (JOURNAL) |
| Journal identifiers | ISSN: 1751-0759 • E-ISSN: 1751-0759 |
| Publisher | Springer Science and Business Media LLC (PUBLISHER) |
| DOI | 10.1186/s13030-022-00235-4 |
| PMID | 35255948 |
| OpenAlex | W4220966470 |
| Language | EN |
| References cited | 41 |
BACKGROUND: Persistent postural-perceptual dizziness (PPPD) is a chronic functional dizziness symptom triggered by psychological stress, but its pathophysiology is unknown. Central sensitization is considered the cause of functional diseases, such as medically unexplained symptoms, and is a psychosocially affected condition. However, the association between dizziness symptoms in PPPD and central sensitization remains unclear. Thus, we conducted a cross-sectional study on the relation between dizziness symptoms and central sensitization in PPPD. METHODS: We recruited 61 outpatients with dizziness who met the PPPD diagnostic criteria. In addition to the evaluation of dizziness symptoms using the Dizziness Handicap Inventory, the participants were evaluated using the Hospital Anxiety and Depression Scale, Pittsburgh Sleep Quality Index, and Central Sensitization Inventory (CSI). A CSI score of 40 or higher was defined as central sensitization syndrome (CSS), and the severity of each condition in CSS and non-CSS participants was compared. We also evaluated the association between dizziness symptoms and central sensitization and coexisting symptoms using linear multiple regression analysis. RESULTS: We analyzed the data of 50 valid responses (valid response rate of 82.0 percent). Compared with the non-CSS group, the CSS group had a higher degree of disability owing to dizziness and a higher rate of complications of anxiety and depression. The regression analysis results showed that the severity of central sensitization was a related factor that could enhance the dizziness symptoms of PPPD. CONCLUSIONS: Central sensitization may affect the dizziness symptoms of PPPD as an exacerbating factor
Anxiety · Central sensitization · Physical therapy · Psychiatry · Sensitization · Balance, Gait, and Falls Prevention · Medicine · Tactile and Sensory Interactions · Vestibular and auditory disorders · Internal Medicine
Depression and Quality of Life in Older Persons
Investigation of the freely available easy-to-use software ‘EZR’ for medical statistics
The validity of the Hospital Anxiety and Depression Scale
The Pittsburgh sleep quality index
The Hospital Anxiety and Depression Scale
Effect of relaxation therapy on benzodiazepine use in patients with medically unexplained symptoms
| Citation velocity | historical |
|---|---|
| Highly cited | No |