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Immunization practices in low birth weight infants from rural Haryana, India

Findings from secondary data analysis

Bibliographic Data

ID19550702
AuthorsRavi Prakash Upadhyay (0000-0003-0767-9637, Society for Applied Studies), Ranadip Chowdhury (0000-0002-0055-6653, Society for Applied Studies), Sarmila Mazumder (0000-0003-4200-6112, Society for Applied Studies), Sunita Taneja (0000-0003-3338-9799, Society for Applied Studies), Bireshwar Sinha (0000-0002-7408-7474, Society for Applied Studies), Jose Martines (University of Bergen), Roy Bahl (0000-0001-7936-6985, World Health Organization), Rajiv Bahl, Neeraj Bhandari (0000-0003-0349-087X, Society for Applied Studies), Nita Bhandari, Maharaj Kishan Bhan (0000-0002-1408-1310, Biotechnology Industry Research Assistance Council)
Year2017
Volume7
Issue2
Pages020415-020415
Publication date2017-12-01
Open AccessYes
TypeARTICLE
VenueJournal of Global Health (JOURNAL)
Journal identifiersISSN: 2047-2978 • E-ISSN: 2047-2986
PublisherInternational Society of Global Health (PUBLISHER • GB)
DOI10.7189/jogh.07.020415
PMID29423177
OpenAlexW2777377047
LanguageEN
Citations received1
References cited33

BACKGROUND: Low birth weight (LBW) infants constitute a vulnerable subset of infants with impaired immunity in early life. In India, there is scarcity of studies that focus on immunization practices in such infants. This analysis aimed to examine immunization practices in LBW infants with the intention to identify areas requiring intervention. METHODS: Data on immunization status of LBW infants enrolled in an individually randomized, double-masked, placebo-controlled trial of neonatal vitamin A supplementation were analysed. Study outcomes were full immunization by one year of age and delayed vaccination with DPT1 and DPT3. Multivariable logistic regression was performed to identify factors associated with the outcome(s). FINDINGS: Out of 10 644 LBW infants enrolled in trial, immunization data were available for 10 517 (98.8%). Less than one-third (29.7%) were fully immunized by one year of age. Lowest wealth quintile (adjusted odds ratio (AOR) 0.39, 95% confidence interval (CI) 0.32-0.47), Muslim religion (AOR 0.41, 95% CI 0.35-0.48) and age of mother <20 years (AOR 0.62, 95% CI 0.52-0.73) were associated with decreased odds of full immunization. Proportion of infants with delayed vaccination for DPT1 and DPT3 were 52% and 81% respectively. Lowest wealth quintiles (AOR 1.51, 95% CI 1.25-1.82), Muslim religion (AOR 1.41, 95% CI 1.21-1.65), mother aged <20 years (AOR 1.31, 95% CI 1.11-1.53) and birth weight <2000 g (AOR 1.20, 95% CI 1.03-1.40) were associated with higher odds of delayed vaccination for DPT-1. Maternal education (≥12 years of schooling) was associated with high odds of full immunization (AOR 2.39, 95% CI 1.97-2.91) and low odds of delayed vaccination for both DPT-1 (AOR 0.59, 95% CI 0.49-0.73) and DPT-3 (AOR 0.57, 95% CI 0.43-0.76). CONCLUSION: In this population, LBW infants are at a risk of delayed and incomplete immunization and therefore need attention. The risks are even higher in identified subgroups that should specifically be targeted

Birth weight · Confidence interval · Immune system · Immunization · Logistic regression · Low birth weight · Odds ratio · Pregnancy · Vaccination · COVID-19 Impact on Reproduction · Demography · Immune responses and vaccinations · Medicine · Vaccine Coverage and Hesitancy · Immunology · Internal Medicine · Pediatrics

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Citations per year0.25
Citation span2022 - 2022 (1)
Highly citedNo

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