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Cost of management of severe pneumonia in young children

Systematic analysis

Bibliographic Data

ID19552190
AuthorsShanshan Zhang (0000-0002-0623-986X, Peking University), Peter M Sammon (University of Edinburgh), Isobel King (University of Edinburgh), Ana Lúcia Andrade (0000-0002-5911-5158, Universidade Federal de Goiás), Cristiana Maria Toscano (0000-0002-9453-2643, Universidade Federal de Goiás), Sheila N Araujo (Universidade Federal de Goiás), Anushua Sinha (Rutgers, the State University of New Jersey), Shabir A Madhi (0000-0002-7629-0636, Respiratory and Meningeal Pathogens Research Unit), Gulam Khandaker (0000-0002-0661-4113, The University of Sydney), J Kevin Yin (0000-0001-5396-3992, Children's Hospital at Westmead), Robert Booy (0000-0002-1953-7452, Children's Hospital at Westmead), Tanvir M Huda (0000-0002-8996-4361, The University of Sydney), Qazi Sadeq-ur Rahman (0000-0003-2650-4904, International Centre for Diarrhoeal Disease Research), Qazi S Rahman, Shams El Arifeen (0000-0002-5372-5932, International Centre for Diarrhoeal Disease Research), Ángela Gentile (0000-0002-1072-7700, Universidad de Buenos Aires), Norberto Giglio (0000-0002-4388-8148, Universidad de Buenos Aires), Mejbah U Bhuiyan, Mejbah Bhuiyan (0000-0002-8274-6265, International Centre for Diarrhoeal Disease Research), Katharine Sturm–Ramirez, Katharine Sturm‐Ramirez (Centers for Disease Control and Prevention), Bradford D Gessner (0000-0002-6216-7194, Agence de Médecine Préventive), Mardiati Nadjib (0000-0001-8676-7525, University of Indonesia), Phyllis J Carosone–Link, Phyllis Carosone‐Link (0000-0001-9128-3189, University of Edinburgh), Eric AF Simões, Eric A F Simões (0000-0001-5588-2723, Colorado School of Public Health), Jason A Child, Jason Child (Children's Hospital Colorado), Imran Ahmed (0000-0001-7425-3113, Aga Khan University), Zulfiqar A Bhutta (0000-0003-0637-599X, Aga Khan University), Sajid Soofi (0000-0003-4192-8406, Aga Khan University), Sajid B Soofi, Rumana J Khan, Rumana Khan (0000-0001-6399-7758, BRAC University), Harry Campbell (0000-0002-6169-6262, University of Edinburgh), Harish Nair (0000-0002-9432-9100, University of Edinburgh, corresponding author)
Year2016
Volume6
Issue1
Pages010408-010408
Publication date2016-06-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Global Health (JOURNAL)
Journal identifiersISSN: 2047-2978 • E-ISSN: 2047-2986
PublisherInternational Society of Global Health (PUBLISHER • GB)
DOI10.7189/jogh.06.010408
PMID27231544
OpenAlexW2396310523
LanguageEN
Citations received20
References cited27

BACKGROUND: Childhood pneumonia is a major cause of childhood illness and the second leading cause of child death globally. Understanding the costs associated with the management of childhood pneumonia is essential for resource allocation and priority setting for child health. METHODS: We conducted a systematic review to identify studies reporting data on the cost of management of pneumonia in children younger than 5 years old. We collected unpublished cost data on non-severe, severe and very severe pneumonia through collaboration with an international working group. We extracted data on cost per episode, duration of hospital stay and unit cost of interventions for the management of pneumonia. The mean (95% confidence interval, CI) and median (interquartile range, IQR) treatment costs were estimated and reported where appropriate. RESULTS: We identified 24 published studies eligible for inclusion and supplemented these with data from 10 unpublished studies. The 34 studies included in the cost analysis contained data on more than 95 000 children with pneumonia from both low- and-middle income countries (LMIC) and high-income countries (HIC) covering all 6 WHO regions. The total cost (per episode) for management of severe pneumonia was US$ 4.3 (95% CI 1.5-8.7), US$ 51.7 (95% CI 17.4-91.0) and US$ 242.7 (95% CI 153.6-341.4)-559.4 (95% CI 268.9-886.3) in community, out-patient facilities and different levels of hospital in-patient settings in LMIC. Direct medical cost for severe pneumonia in hospital inpatient settings was estimated to be 26.6%-115.8% of patients' monthly household income in LMIC. The mean direct non-medical cost and indirect cost for severe pneumonia management accounted for 0.5-31% of weekly household income. The mean length of stay (LOS) in hospital for children with severe pneumonia was 5.8 (IQR 5.3-6.4) and 7.7 (IQR 5.5-9.9) days in LMIC and HIC respectively for these children. CONCLUSION: This is the most comprehensive review to date of cost data from studies on the management of childhood pneumonia and these data should be helpful for health services planning and priority setting by national programmes and international agencies

Confidence interval · Intensive care medicine · Interquartile range · Pneumonia · Psychological intervention · Global Maternal and Child Health · Medicine · Nursing · Pneumonia and Respiratory Infections · Respiratory viral infections research · Emergency Medicine · Internal Medicine · Pediatrics

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Unique citing works20
Citations per year2,22
Citation span2017 - 2026 (10)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 20
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