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The Predictive Influence of Self-Efficacy and Socioeconomic Factors on the Physical and Mental Health-Related Quality of Life of Adolescents and Young Adults with Sickle Cell Disease

Bibliographic Data

ID19588487
AuthorsAkinpelu Tomiwa (University of Ibadan, corresponding author)
Year2025
Volume8
Issue2
Pages98-113
Publication date2025-06-11
Open AccessYes
TypeARTICLE
VenueAfrican Journal of Social Sciences and Humanities Research (JOURNAL)
Journal identifiersISSN: 2689-5129 • E-ISSN: 2689-5129
PublisherAfrican - British Journals (PUBLISHER)
DOI10.52589/ajsshr-gjvajzmn
OpenAlexW4411193835
LanguageEN
References cited54

Sickle cell disease (SCD), an inherited disorder of haemoglobin, is associated with severe physical and psychological burdens, both of which are influenced by a wide range of cognitive and socio-environmental factors. The current study aimed to establish the predictive influence of self-efficacy and family socioeconomic factors on the physical and mental health-related quality of life (HRQoL) of adolescents and young adults (AYA) with SCD. A cross-sectional study design was adopted, involving a sample of 116 AYAs with SCD, aged 16 to 24, recruited from two health facilities in South-West Nigeria. Participants completed assessments of SCD self-efficacy using the Sickle Cell Self-Efficacy Scale (SCSES) and HRQoL using the physical and mental component summary measures of the Short-Form 36 (SF-36). Family socioeconomic factors and socioeconomic status were evaluated using a Family Socioeconomic Status Scale adopted for the study. Multiple regression analysis indicated a significant joint influence of self-efficacy and socioeconomic factors on both physical and mental HRQoL, accounting for 64% variance in physical HRQoL and 66% variance in mental HRQoL. All evaluated variables, except home sanitation, independently predicted physical HRQoL, while all variables, except education and occupation, independently predicted mental HRQoL. Family possession, family-specific factors, and home sanitation were the most significant socioeconomic predictors of both physical and mental HRQoL. Moderation analysis indicated that socioeconomic status significantly moderated the influence of self-efficacy on mental HRQoL but not on physical HRQoL. The study highlights the need for exploring comprehensive and multi-faceted approaches in the management of SCD that go beyond medical treatment to address the broader social and psychological factors that influence physical and mental HRQoL

Developmental psychology · Disease · Environmental health · Mental health · Population · Psychiatry · Psychotherapist · Self-efficacy · Socioeconomic status · Clinical Psychology · Health and Wellbeing Research · Health disparities and outcomes · Hemoglobinopathies and Related Disorders · Medicine · Psychology · Social Psychology · Gerontology · Internal Medicine

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