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Vaccine wastage rates and attributed factors in rural and urban areas in Uganda

Case of Mukono and Kalungu districts

Bibliographic Data

ID19590976
AuthorsMackline Ninsiima (0009-0008-1081-3124, Makerere University, corresponding author), Michael Muhoozi (0000-0003-2460-9980, Makerere University, corresponding author), Henry Luzze (0000-0002-8747-9995, Ministry of Health, corresponding author), Simon Kasasa (0000-0002-0592-0709, Makerere University, corresponding author)
EditorsJulia Robinson (0000-0003-0719-3995)
Year2025
Volume5
Issue6
Pagese0003745
Publication date2025-06-10
Open AccessYes
TypeARTICLE
VenuePLOS Global Public Health (JOURNAL)
Journal identifiersISSN: 2767-3375 • E-ISSN: 2767-3375
PublisherPublic Library of Science (PLoS) (PUBLISHER)
DOI10.1371/journal.pgph.0003745
PMID40493663
OpenAlexW4411173937
LanguageEN
References cited18

Vaccine wastage remains a challenge to effective immunization; especially in low-income countries. We estimated vaccine wastage rates and assessed attributed factors in Mukono and Kalungu districts in Uganda. A mixed methods study design was utilised to estimate vaccine wastage rates for BGC, OPV, IPV, PCV, MR, DPT–HepB–Hib for 6 months prospectively from March–August 2022 and assess attributed factors in 22 health facilities. Mann–Kendall statistical test was used to assess significance of observed trends. We applied Mann Whitney U and Kruskal–Wallis H tests to compare vaccine wastage rates per vaccine by district, ownership, and type of health facility. Additionally, we administered a questionnaire among 57 health workers and conducted 15 Key Informant Interviews to understand reasons for vaccine wastage. Overall vaccine wastage rates were BCG (70%), MR (58%), DPT–HepB–Hib (21%), IPV (31%), OPV (28%) and PCV (17%); exceeding accepted vaccine wastage rates in Kalungu and Mukono districts. Significant variations were observed across the different types of health facilities [BCG (p

Geography · Political science · Rural area · Socioeconomics · Sociology · Animal Disease Management and Epidemiology · Hepatitis Viruses Studies and Epidemiology · Law · Vaccine Coverage and Hesitancy

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