Understanding the fine-scale heterogeneity and spatial drivers of malaria transmission in Kenya using model-based geostatistical methods
Bibliographic Data
| ID | 19591293 |
|---|---|
| Authors | Donnie Mategula (0000-0001-7109-9042, University of Liverpool, corresponding author), Judy Gichuki (0000-0003-2519-6225, Strathmore University, corresponding author) |
| Editors | Collins Otieno Asweto (0000-0003-3514-9836) |
| Year | 2023 |
| Volume | 3 |
| Issue | 12 |
| Pages | e0002260 |
| Publication date | 2023-12-08 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | PLOS Global Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2767-3375 • E-ISSN: 2767-3375 |
| Publisher | Public Library of Science (PLoS) (PUBLISHER) |
| DOI | 10.1371/journal.pgph.0002260 |
| PMID | 38064427 |
| OpenAlex | W4389475740 |
| Language | EN |
| References cited | 11 |
Malaria remains a public health concern. Monitoring the fine-scale heterogeneity of the malaria burden enables more targeted control efforts. Although malaria indicator surveys (MIS) have been crucial in evaluating the progress of malaria control interventions, they are only designed to provide a cross-sectional national and regional malaria disease burden. Recent advances in geostatistical methods allow us to interpolate national survey data to describe subnational disease burden that is crucial in informing targeted control. A binomial geostatistical model employing Markov chain Monte Carlo (MCMC) parameter estimation methods is used to understand the spatial drivers of malaria risk in Kenya and to predict malaria risk at a fine-scale resolution, including identifying hotspots. A total of 11,549 children aged six months to 14 years from 207 clusters were sampled in this survey and used in the present analysis. The national malaria prevalence based on the data was 8.4%, with the highest in the lake endemic zone (18.1%) and the lowest in the low-risk zone (
Biology · Environmental health · Geography · Indoor residual spraying · Malaria · Plasmodium falciparum · Urbanization · Livestock and Poultry Management · Malaria Research and Control · Medicine · Mosquito-borne diseases and control · Ecology
| Highly cited | No |
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