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Investigating clinic transfers among HIV patients considered lost to follow-up to improve understanding of the HIV care cascade

Findings from a cohort study in rural north-eastern South Africa

Bibliographic Data

ID19591544
AuthorsDavid Etoori (0000-0002-2807-6272, London School of Hygiene & Tropical Medicine, corresponding author), Chodziwadziwa Kabudula (0000-0002-5867-0336, University of the Witwatersrand), Alison Wringe (0000-0001-6939-3461, London School of Hygiene & Tropical Medicine), Brian Rice (0000-0002-5416-8058, London School of Hygiene & Tropical Medicine), Jenny Renju (0000-0001-5650-1902, London School of Hygiene & Tropical Medicine), Francesc Xavier Gómez-Olivé (0000-0002-4876-0848, University of the Witwatersrand), Georges Reniers (0000-0001-6582-1692, University of the Witwatersrand)
EditorsRuwan Ratnayake (0000-0003-4978-6668)
Year2022
Volume2
Issue5
Pagese0000296
Publication date2022-05-24
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenuePLOS Global Public Health (JOURNAL)
Journal identifiersISSN: 2767-3375 • E-ISSN: 2767-3375
PublisherPublic Library of Science (PLoS) (PUBLISHER)
DOI10.1371/journal.pgph.0000296
PMID36962304
OpenAlexW4281395735
LanguageEN
Citations received6
References cited59

Investigating clinical transfers of HIV patients is important for accurate estimates of retention and informing interventions to support patients. We investigate transfers for adults reported as lost to follow-up (LTFU) from eight HIV care facilities in the Agincourt health and demographic surveillance system (HDSS), South Africa. Using linked clinic and HDSS records, outcomes of adults more than 90 days late for their last scheduled clinic visit were determined through clinic and routine tracing record reviews, HDSS data, and supplementary tracing. Factors associated with transferring to another clinic were determined through Cox regression models. Transfers were graphically and geospatially visualised. Transfers were more common for women, patients living further from the clinic, and patients with higher baseline CD4 cell counts. Transfers to clinics within the HDSS were more likely to be undocumented and were significantly more likely for women pregnant at ART initiation. Transfers outside the HDSS clustered around economic hubs. Patients transferring to health facilities within the HDSS may be shopping for better care, whereas those who transfer out of the HDSS may be migrating for work. Treatment programmes should facilitate transfer processes for patients, ensure continuity of care among those migrating, and improve tracking of undocumented transfers

Cohort · Cohort study · Family medicine · Health care · Proportional hazards model · Psychological intervention · Global Maternal and Child Health · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Medicine · Nursing · Internal Medicine · Surgery

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Unique citing works6
Citations per year3
Citation span2024 - 2025 (2)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 6
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