Association between adverse childhood experiences and type 2 diabetes mellitus in later life
A case-control study
Bibliographic Data
| ID | 19591965 |
|---|---|
| Authors | Nilima Barman (0000-0001-9664-5636, University of Dhaka, corresponding author), Abul B M M K Islam (0000-0002-7274-0855, University of Dhaka, corresponding author), M Atiqul Haque (0000-0002-7598-2550, Bangladesh Medical University, corresponding author) |
| Editors | Dickson Abanimi Amugsi |
| Year | 2024 |
| Volume | 4 |
| Issue | 6 |
| Pages | e0002715 |
| Publication date | 2024-06-25 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | PLOS Global Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2767-3375 • E-ISSN: 2767-3375 |
| Publisher | Public Library of Science (PLoS) (PUBLISHER) |
| DOI | 10.1371/journal.pgph.0002715 |
| PMID | 38917185 |
| OpenAlex | W4400019112 |
| Language | EN |
| References cited | 38 |
Adverse childhood experiences (ACEs) are potentially traumatic events that occur before 18 years of age. Studies emphasize the importance of childhood adversity as a risk factor for developing non-communicable diseases, including type-2 diabetes mellitus (T2DM) in adulthood. This case-control study involved 137 patients with T2DM and 134 non-diabetic adults of both genders (mean age 46.9 and 45.7 years, respectively). In addition to collecting socio-demographic, behavioral, and anthropological data, a 10-item ACE scale was utilized to gather information regarding childhood adversities, while perceived stress was assessed using the perceived stress scale-4. Fasting and 2-hour post glucose load blood sugar levels, HbA1c, and fasting lipid profiles were measured. Both univariable and multivariable binary logistic regression analyses were performed to investigate whether ACE is a potential risk factor for T2DM, with a significance level of 0.05. Around two-thirds of T2DM patients reported having ACE scores of 4 or higher, with the mean ACE score significantly higher in the case group than in the control group (3.96 vs. 3.34; p
Confounding · Diabetes mellitus · Dyslipidemia · Family history · Logistic regression · Protective factor · Risk factor · Type 2 Diabetes Mellitus · Birth, Development, and Health · Child Abuse and Trauma · Demography · Medicine · Prenatal Substance Exposure Effects · Endocrinology · Internal Medicine
Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge
Biological embedding of childhood adversity
Child abuse
The adverse childhood experiences questionnaire
Obesity and Type 2 Diabetes Risk in Midadult Life
The Lifelong Effects of Early Childhood Adversity and Toxic Stress
The effect of multiple adverse childhood experiences on health
Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults
Validity and reliability of the 10-Item Adverse Childhood Experiences Questionnaire (ACE-10) among adolescents in the child welfare system
Adverse childhood events and risk of diabetes onset in the 1979 National longitudinal survey of youth cohort
Psychological stress in childhood and susceptibility to the chronic diseases of aging
A Global Measure of Perceived Stress
| Highly cited | No |
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