HPV knowledge and non-adherence to cervical cancer screening before and following the Covid-19 pandemic in the United States
Bibliographic Data
| ID | 19592280 |
|---|---|
| Authors | Mariah Malak Bilalaga (0000-0002-1598-8627, Georgetown University, corresponding author), Greeshma Gaddipati (Georgetown University, corresponding author), Anirudra Devkota (0000-0002-6010-4640, Georgetown University, corresponding author), Ramya Vasireddy (Georgetown University, corresponding author), Ted Akhiwu (0000-0002-8594-9658, Georgetown University, corresponding author), Atarere Joseph (0000-0002-7224-2194, Georgetown University, corresponding author), Joseph Atarere, Boniface Mensah (Georgetown University, corresponding author), Christopher Haas (0000-0002-6513-2085, Georgetown University, corresponding author), Louay Almidani (0009-0001-6769-5519, Johns Hopkins University, corresponding author) |
| Editors | Nnodimele Onuigbo Atulomah (0000-0002-4803-503X) |
| Year | 2025 |
| Volume | 5 |
| Issue | 9 |
| Pages | e0004800 |
| Publication date | 2025-09-10 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | PLOS Global Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2767-3375 • E-ISSN: 2767-3375 |
| Publisher | Public Library of Science (PLoS) (PUBLISHER) |
| DOI | 10.1371/journal.pgph.0004800 |
| PMID | 40929021 |
| OpenAlex | W4414111746 |
| Language | EN |
| References cited | 19 |
To compare HPV vaccination knowledge and non-adherence rates to cervical cancer screening in a nationally representative sample of American women before and following the COVID-19 pandemic, female participants aged 21–65 years from the National Cancer Institute Health Information National Trends Survey 2019 and 2022 were included. Adherence to cervical cancer screening was assessed based on the timing of their last Papanicolaou (PAP) smear, with participants classified as non-adherent to cervical cancer guidelines if their last PAP smear was > 3 years. Further, participants were asked about their knowledge of the HPV vaccine and were categorized as unaware if they had not heard of it before. Survey-weighted Poisson regression models adjusted for age, race, and education were used to explore both adherence and HPV vaccination knowledge before and following the COVID-19 pandemic. We included 1,905 females with a mean age of 44.5 years, 61.3% were White, and 35.4% had a college education or higher. The prevalence of non-adherence in 2019 was 19.2% and increased by 6.6% in 2022. White adults showed an increase of 5.6%, while Black adults showed an increase of 13.9%. When exploring changes in HPV vaccination knowledge, 18.9% did not hear about the HPV vaccine in 2019, which slightly increased by 2.8% in 2022. Being Black and having lower education were significantly associated with both greater non-adherence rates and not hearing about HPV vaccine. Non-adherence to cervical cancer screening increased following the COVID-19 pandemic, especially amongst under-represented communities including Black adults and those with lower education. This trend was also reflected in reduced awareness of HPV vaccination. Further studies are needed to elucidate barriers associated with greater non-adherence rates and to explore targeted interventions, such as educational campaigns, community outreach programs, and initiatives to improve access for underserved populations, which may promote more equitable screening uptake and healthcare access
Cancer · Cancer screening · Cervical cancer · Cervical cancer screening · Health Information National Trends Survey · Pandemic · Papanicolaou stain · Poisson regression · Vaccination · Cervical Cancer and HPV Research · Genital Health and Disease · Global Cancer Incidence and Screening
| Citation velocity | historical |
|---|---|
| Highly cited | No |