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The National Covid-19 Epi Model (NCEM)

Estimating cases, admissions and deaths for the first wave of Covid-19 in South Africa

Bibliographic Data

ID19592302
AuthorsSheetal Silal (0000-0002-3007-5383, University of Cape Town, corresponding author), Juliet R C Pulliam (0000-0003-3314-8223, Stellenbosch University, corresponding author), Gesine Meyer‐Rath (0000-0003-0439-381X, Boston University, corresponding author), Lise Jamieson (0000-0003-2354-4580, University of the Witwatersrand, corresponding author), Brooke E Nichols (0000-0003-4682-4999, Boston University, corresponding author), Jared Norman (0000-0002-5692-999X, University of Cape Town, corresponding author), Rachel Hounsell (0000-0003-1393-4294, University of Cape Town, corresponding author), Saadiyah Mayet (0000-0001-8408-1394, University of Cape Town, corresponding author), Frank Kagoro (0000-0003-4608-7167, University of Cape Town, corresponding author), Harry Moultrie (0000-0001-9722-0699, National Health Laboratory Service, corresponding author)
EditorsMarguerite Massinga Loembe (0000-0002-7822-566X)
Year2023
Volume3
Issue4
Pagese0001070
Publication date2023-04-24
Open AccessYes
TypeARTICLE
VenuePLOS Global Public Health (JOURNAL)
Journal identifiersISSN: 2767-3375 • E-ISSN: 2767-3375
PublisherPublic Library of Science (PLoS) (PUBLISHER)
DOI10.1371/journal.pgph.0001070
PMID37093784
OpenAlexW4366819626
LanguageEN
Citations received2
References cited7

In March 2020 the South African COVID-19 Modelling Consortium was formed to support government planning for COVID-19 cases and related healthcare. Models were developed jointly by local disease modelling groups to estimate cases, resource needs and deaths due to COVID-19. The National COVID-19 Epi Model (NCEM) while initially developed as a deterministic compartmental model of SARS-Cov-2 transmission in the nine provinces of South Africa, was adapted several times over the course of the first wave of infection in response to emerging local data and changing needs of government. By the end of the first wave, the NCEM had developed into a stochastic, spatially-explicit compartmental transmission model to estimate the total and reported incidence of COVID-19 across the 52 districts of South Africa. The model adopted a generalised Susceptible-Exposed-Infectious-Removed structure that accounted for the clinical profile of SARS-COV-2 (asymptomatic, mild, severe and critical cases) and avenues of treatment access (outpatient, and hospitalisation in non-ICU and ICU wards). Between end-March and early September 2020, the model was updated 11 times with four key releases to generate new sets of projections and scenario analyses to be shared with planners in the national and provincial Departments of Health, the National Treasury and other partners. Updates to model structure included finer spatial granularity, limited access to treatment, and the inclusion of behavioural heterogeneity in relation to the adoption of Public Health and Social Measures. These updates were made in response to local data and knowledge and the changing needs of the planners. The NCEM attempted to incorporate a high level of local data to contextualise the model appropriately to address South Africa’s population and health system characteristics that played a vital role in producing and updating estimates of resource needs, demonstrating the importance of harnessing and developing local modelling capacity

Disease · Geography · Public health · Telecommunications · Treasury · Computer Science · COVID-19 epidemiological studies · demographic modeling and climate adaptation · Demography · Health disparities and outcomes · Medicine

  • Differential in-hospital mortality and intensive care treatment over time

    Open Access•Lise Jamieson, Cari van Schalkwyk et al.•PLOS Global Public Health•2023

  • The role of modelling and analytics in South African Covid-19 planning and budgeting

    Open Access•Gesine Meyer‐Rath, Rachel Hounsell et al.•PLOS Global Public Health•2023

  • Differential in-hospital mortality and intensive care treatment over time

    Open Access•Lise Jamieson, Cari van Schalkwyk et al.•PLOS Global Public Health•2023

Citations per year0.67
Citation span2023 - 2023 (1)
Highly citedNo

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