India may need an additional metric to assess the endemicity of malaria in low surveillance districts

Dados Bibliográficos

ID19592534
AutoresChander Prakash Yadav (0000-0001-7531-6307, National Institute of Malaria Research), Sanjeev Gupta (0000-0002-9660-6597), Sanjeev Kumar Gupta (0000-0001-7583-2301, National Institute of Malaria Research), Praveen K Bharti (0000-0003-1511-7503, National Institute of Malaria Research), Manju Rahi (0000-0003-0932-0935, Indian Council of Medical Research), Nafis Faizi (0000-0002-4634-6790, Jawaharlal Nehru Medical College Hospital), Amit Sharma (0000-0001-6130-1913, International Centre for Genetic Engineering and Biotechnology, autor correspondente)
EditoresLouisa Alexandra Messenger
Ano2022
Volume2
Fascículo11
Páginase0000326
Data de publicação2022-11-10
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoPLOS Global Public Health (JOURNAL)
Identificadores do periódicoISSN: 2767-3375 • E-ISSN: 2767-3375
EditoraPublic Library of Science (PLoS) (PUBLISHER)
DOI10.1371/journal.pgph.0000326
PMID36962502
OpenAlexW4308701011
IdiomaEN
Citações recebidas2
Referências citadas10

India’s National Framework for malaria elimination is essentially dependent on Annual Parasite Incidence (API). API is the primary criterion for classifying states and districts into different categories: intensified control, pre-elimination, elimination, prevention and re-establishment of malaria. However, API’s validity is critically dependent on multiple factors, one such important factor is Annual Blood Examination Rate (ABER) and is often considered as indicator of operational efficiency. Therefore, the present study aimed to determine whether the API is a sufficiently good malaria index to assess malaria endemicity in India. An in-depth analysis of malaria data (2017–19) was done to determine the appropriateness of API as a sole indicator of malaria endemicity. We stratified the Indian districts into three strata based on Annual Blood Examination Rate (ABER): 15, further APIs was compared with Slide Positivity Rates (SPRs) using sign rank test, independently in each stratum. API and SPR were found comparable (p-value 0.323) in stratum 2 only. However, in the case of lower ABER ( 15%), the API was found substantially higher than the SPR. Thus, ABER tunes the validity of API and should avoid to use as a single indicator of malaria endemicity. API is an appropriate measure of malaria endemicity in high and moderate transmission areas where surveillance is good (ABER≥5%). However, it is vitally dependent upon surveillance rate and other factors such as population size, the selection of individuals for malaria testing. Therefore, where surveillance is poor (

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