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Meeting the 2030 END TB goals in the wake of Covid-19

A modelling study of countries in the Usaid TB portfolio

Bibliographic Data

ID19593585
AuthorsNimalan Arinaminpathy (0000-0001-9502-6876, Imperial College London, corresponding author), Ya Diul Mukadi (0000-0001-9713-1557, United States Agency for International Development, corresponding author), Amy Bloom (United States Agency for International Development, corresponding author), Cheri Vincent (United States Agency for International Development, corresponding author), Sevim Ahmedov (0000-0001-6564-3638, United States Agency for International Development, corresponding author)
EditorsHsiang-Yu Yuan (0000-0003-0061-0012)
Year2023
Volume3
Issue10
Pagese0001271
Publication date2023-10-23
Open AccessYes
TypeARTICLE
VenuePLOS Global Public Health (JOURNAL)
Journal identifiersISSN: 2767-3375 • E-ISSN: 2767-3375
PublisherPublic Library of Science (PLoS) (PUBLISHER)
DOI10.1371/journal.pgph.0001271
PMID37870997
OpenAlexW4387873697
LanguageEN
Citations received2
References cited13

Progress towards the 2030 End TB goals has seen severe setbacks due to disruptions arising from the COVID-19 pandemic. For governments and international partner organizations supporting the global TB response, there is a need to assess what level of effort is now needed to reach these goals. Using mathematical modelling, we addressed this question for the countries being supported by the United States Agency for International Development (USAID). We aggregated the 24 countries in the USAID portfolio into three geographical country groups: South Asia; sub-Saharan Africa; and Central Asian Republics/Europe (CAR/EU). From 2023 onwards we modelled a combination of interventions acting at different stages of the care cascade, including improved diagnostics; reducing the patient care seeking delay; and the rollout of a disease-preventing vaccine from 2025 onwards. We found that in all three country groups, meeting the End TB goals by 2030 will require a combination of interventions acting at stages of the TB care cascade. Specific priorities may depend on country settings, for example with public-private mix playing an important role in countries in South Asia and elsewhere. When a vaccine becomes available, its required coverage to meet the 2030 goals will vary by setting, depending on the amount of preventive therapy that has already been implemented. Monitoring the number-needed-to-test to identify 1 person with TB in community settings can provide a useful measure of progress towards the End TB goals

Business · Developing country · Development economics · Disease · Economic growth · Economics · Pandemic · Political science · Portfolio · Psychological intervention · Sociology · Medicine · Nursing · Pneumocystis jirovecii pneumonia detection and treatment · Pneumonia and Respiratory Infections · Tuberculosis Research and Epidemiology · Finance

  • Towards ending tuberculosis in South Africa

    Open Access•Leigh F Johnson, Mmamapudi Kubjane et al.•Global Health Action•2026

  • Mapping the existing body of knowledge on new and repurposed TB vaccine implementation

    Open Access•Joeri S Buis, Degu Jerene et al.•PLOS Global Public Health•2024

  • Ending TB in Southeast Asia

    Open Access•Vineet Bhatia, Rahul Srivastava et al.•BMJ Global Health•2020

Citations per year1
Citation span2024 - 2026 (3)
Highly citedNo

Tools

Open DOIOpen Access
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