Prevalence and determinants of low testosterone levels in men with type 2 diabetes mellitus; a case-control study in a district hospital in Ghana
Bibliographic Data
| ID | 19593753 |
|---|---|
| Authors | Dorcas Serwaa (0000-0001-8583-4415, University of Ibadan, corresponding author), Folasade Adenike Bello (0000-0002-3337-3335, University of Ibadan, corresponding author), Kayode O Osungbade (0000-0001-5423-912X, University College Hospital, Ibadan, corresponding author), Charles Nkansah (0000-0001-6986-9976, University for Development Studies, corresponding author), Felix Osei-Boakye (0000-0001-5126-7424, Sunyani Technical University, corresponding author), Samuel Kwasi Appiah (0000-0003-1855-5840, University for Development Studies, corresponding author), Maxwell Hubert Antwi (0000-0002-5997-9829, corresponding author), Mark Danquah (0000-0002-0464-2313, Sunyani Technical University, corresponding author), Tonnies Abeku Buckman (0000-0003-0425-4481, Kwame Nkrumah University of Science and Technology, corresponding author), Ernest Owusu (0000-0003-1231-4501, corresponding author) |
| Editors | Palash Chandra Banik (0000-0003-2395-9049) |
| Year | 2021 |
| Volume | 1 |
| Issue | 12 |
| Pages | e0000052 |
| Publication date | 2021-12-02 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | PLOS Global Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2767-3375 • E-ISSN: 2767-3375 |
| Publisher | Public Library of Science (PLoS) (PUBLISHER) |
| DOI | 10.1371/journal.pgph.0000052 |
| PMID | 36962255 |
| OpenAlex | W4200047182 |
| Language | EN |
| Citations received | 1 |
| References cited | 37 |
Diabetes mellitus, an endocrine disorder, has been implicated in many including hypogonadism in men. Given the fact that diabetes mellitus is becoming a fast-growing epidemic and the morbidity associated with it is more disabling than the disease itself. This study sought to assess the prevalence of low testosterone levels and predictors in type 2 diabetes mellitus patients and non-diabetic men in a district hospital in Ghana. This hospital-based case-control study comprised 150 type 2 diabetics and 150 healthy men. A pre-structured questionnaire and patient case notes were used to document relevant demographic and clinical information. Venous blood sample of about 6 ml was taken to measure FBS, HbA1c, FSH, LH, and testosterone levels. All data were analyzed using STATA version 12 (STATA Corporation, Texas, USA). The overall hypogonadism in the study population was 48% (144/300). The prevalence of hypogonadism in type 2 diabetic subjects was almost three times more than in healthy men (70.7% vs 25.3%). The odds of having hypogonadism was lower in the men with normal weight and overweight with their underweight counterparts (AOR = 0.33, 95% CI; 0.12–0.96, p = 0.042) and (AOR = 0.29, 95% CI; 0.10–0.84, p = 0.023) respectively. Also, the odds of suffering from hypogonadism was lower in non-smokers compared with smokers (AOR: 0.16, 95% CI; 0.05–0.58, p = 0.005). Participants who were engaged in light (AOR: 0.29, 95% CI; 0.14–0.61, p = 0.001), moderate (AOR: 0.26, 95% CI; 0.13–0.54, p
Diabetes mellitus · Obesity · Odds ratio · Overweight · Population · Type 2 Diabetes Mellitus · Underweight · Hormonal and reproductive studies · Medicine · Pharmacology and Obesity Treatment · Sexual function and dysfunction studies · Endocrinology · Internal Medicine · Pediatrics
| Citations per year | 1 |
|---|---|
| Citation span | 2026 - 2026 (1) |
| Highly cited | No |