Improving maternal and neonatal outcomes among pregnant women who are HIV-positive or HIV-negative through the Saving Mothers Giving Life initiative in Uganda
An analysis of population-based mortality surveillance data
Bibliographic Data
| ID | 19594294 |
|---|---|
| Authors | Maureen Nabatanzi (0000-0002-9801-4210, Ministry of Health, corresponding author), Julie R Harris (0000-0002-2496-8441, Centers for Disease Control and Prevention), Phoebe Namukanja (0000-0002-7570-4091, Centers for Disease Control and Prevention), Steven Ndugwa Kabwama (0000-0002-0354-9571, Makerere University), Sandra Nabatanzi (Centers for Disease Control and Prevention), Phoebe Nabunya (0000-0001-5181-6622, Ministry of Health), Benon Kwesiga (0000-0003-0400-8635, Ministry of Health), Alex Riolexus Ario (0000-0002-3560-1952, Ministry of Health), Patrick Komakech (World Health Organization - Uganda) |
| Editors | Nazmul Alam (0000-0001-6119-8178) |
| Year | 2024 |
| Volume | 4 |
| Issue | 2 |
| Pages | e0002801 |
| Publication date | 2024-02-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | PLOS Global Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2767-3375 • E-ISSN: 2767-3375 |
| Publisher | Public Library of Science (PLoS) (PUBLISHER) |
| DOI | 10.1371/journal.pgph.0002801 |
| PMID | 38300894 |
| OpenAlex | W4391429994 |
| Language | EN |
| References cited | 15 |
HIV infection is associated with poor maternal health outcomes. In 2016, the maternal mortality ratio (MMR) in Uganda was 336/100,000, and the neonatal mortality rate (NMR) was 19/1,000. Saving Mothers, Giving Life (SMGL) was a five-year maternal and neonatal health strengthening initiative launched in 2012 in Uganda. We extracted maternal and neonatal data for 2015–2016 from the initiative’s population-based mortality surveillance system in 123 health facilities in Western Uganda. We collected data on the facilities, HIV status, antiretroviral drug (ARV) use, death, birth weight, delivery type, parity, Apgar scores, and complications. We compared mother and baby outcomes between HIV-positive or HIV-negative, computed risk ratios (RR) for adverse outcomes, and used the chi-square to test for significance in differences observed. Among 116,066 pregnant women who attended and gave birth at SMGL-implementing facilities during 2015–2016, 8,307 (7.7%) were HIV-positive, of whom 7,809 (94%) used antiretroviral drugs (ARVs) at the time of delivery. During birth, 23,993 (21%) women experienced ≥1 complications. Neonate Apgar scores
Apgar score · Birth weight · Confidence interval · Environmental health · Low birth weight · Neonatal sepsis · Obstetrics · Population · Pregnancy · Relative risk · Sepsis · Child Nutrition and Water Access · Global Maternal and Child Health · HIV/AIDS Research and Interventions · Medicine · Immunology · Internal Medicine · Pediatrics
Global, regional, and national levels and causes of maternal mortality during 1990–2013
Delivering maternal and neonatal health interventions in conflict settings
How has sustainable development goals declaration influenced health financing reforms for universal health coverage at the country level? A scoping review of literature
| Citation velocity | historical |
|---|---|
| Highly cited | No |