Viral suppression and associated factors after enhanced adherence counseling among people living with HIV with unsuppressed viral loads at tertiary and first-level health facilities in Zambia
A retrospective cohort study
Bibliographic Data
| ID | 19594392 |
|---|---|
| Authors | Chitalu Chanda (0000-0003-1186-5045, University Teaching Hospital, corresponding author), Webster C Chewe, Webster Chewe (0000-0002-2516-3944, National HIV/AIDS/STI/TB Council, corresponding author), Benson M Hamooya (0000-0003-1385-0998, Mulungushi University, corresponding author), Lukundo Siame (0009-0002-4810-7352, Livingstone Hospital, corresponding author), Matenge Mutalange (Mulungushi University, corresponding author), Aliness Dombola, Aliness M Dombola (National Institute of Public Administration, corresponding author), Nyuma Mbewe (0000-0002-3309-0538, National Institute of Public Administration, corresponding author), Chisha Sinyangwe (University Teaching Hospital, corresponding author), Melvin Mwansa (0000-0002-4120-4574, University of Lusaka, corresponding author), Duncan Chanda (0000-0001-5477-9054, University Teaching Hospital, corresponding author) |
| Editors | Orvalho Augusto (0000-0002-0005-3968) |
| Year | 2025 |
| Volume | 5 |
| Issue | 11 |
| Pages | e0005417 |
| Publication date | 2025-11-05 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | PLOS Global Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2767-3375 • E-ISSN: 2767-3375 |
| Publisher | Public Library of Science (PLoS) (PUBLISHER) |
| DOI | 10.1371/journal.pgph.0005417 |
| PMID | 41191603 |
| OpenAlex | W4415934987 |
| Language | EN |
| References cited | 15 |
People living with HIV (PLHIV) who do not achieve viral suppression on antiretroviral therapy contribute to HIV transmission. Poor adherence is a major factor associated with high viral load (VL). Enhanced adherence counseling (EAC) is a targeted intervention to improve adherence and achieve viral suppression, but data on post-EAC outcomes in Zambia remain limited. This study assessed viral suppression and associated factors among PLHIV with unsuppressed VL after completion of EAC at University Teaching Hospital and Kanyama First-Level Hospital. This retrospective cohort study analyzed VL register data from 1 st January 2021–31 st December 2023. Baseline demographic, clinical, and laboratory data were collected, with follow-up VL measurements at three and 12 months post-EAC. The primary outcome was viral suppression at three months, defined as a VL
Cohort · Cohort study · Lentivirus · Poisson regression · Retrospective cohort study · Viral disease · Viral load · Young adult · HIV Research and Treatment · HIV/AIDS drug development and treatment · HIV/AIDS Research and Interventions
| Citation velocity | historical |
|---|---|
| Highly cited | No |