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Principles and priorities for integrated tuberculosis screening and care

A modified Delphi consensus exercise

Bibliographic Data

ID19594516
AuthorsClaire Jacqueline Calderwood (0000-0002-1926-7464, London School of Hygiene & Tropical Medicine, corresponding author), Tenzin Kunor (Atlanta Research and Education Foundation), Mikaela Coleman (0000-0002-4414-5645, The University of Sydney), Edson Marambire (0000-0001-5944-5010, Biomedical Research and Training Institute), Uzma Khan (0000-0001-7090-7810, Treasury Board of Canada Secretariat), Rosa Herrera (0009-0000-0113-0702, Universidad Autónoma de Baja California), Jeffry Acaba (0000-0002-4807-9040, Social Security Office (Thailand)), Zafar Hussain (London School of Hygiene & Tropical Medicine), Diptendu Bhattacharya (0000-0002-8981-710X, International Union Against Tuberculosis and Lung Disease), Leyla Sophie Larsson (0000-0003-4869-4630, German Center for Infection Research), Leyla Larsson, José Luis Paredes (0000-0002-0547-1376, Advocate Illinois Masonic Medical Center), Laura Paramo (0000-0003-4992-5330, German Center for Infection Research), Marcia Chiluvane (0000-0003-2060-0380, Instituto Nacional de Saúde), Thu Anh Nguyen (0000-0002-2089-2902), Thu-Anh Nguyen, Thu-Anh T Nguyen (The University of Sydney), Hanh Nguyen Hong (0000-0001-8241-9267, Oxford University Clinical Research Unit), Marc d’Elbée (0000-0002-8827-019X, Université de Bordeaux), Eneyi Kpokiri (London School of Hygiene & Tropical Medicine), Luan Nguyen Quang Vo (0000-0002-5937-6286, Karolinska Institutet), Tom Wingfield (0000-0001-8433-6887, University of Liverpool), Ben Marais (The University of Sydney), Madhavi Bhargava (0000-0001-7480-566X, Yenepoya University), Bernay (0000-0001-7628-8408, The University of Sydney), Sarah Bernays, Katharina Kranzer (0000-0001-5691-7270, London School of Hygiene & Tropical Medicine)
EditorsGiorgia Sulis (0000-0001-6641-0094)
Year2026
Volume6
Issue3
Pagese0005954
Publication date2026-03-02
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenuePLOS Global Public Health (JOURNAL)
Journal identifiersISSN: 2767-3375 • E-ISSN: 2767-3375
PublisherPublic Library of Science (PLoS) (PUBLISHER)
DOI10.1371/journal.pgph.0005954
PMID41770762
OpenAlexW7133192243
LanguageEN
References cited23

Tuberculosis predominates in communities with multiple health and socioeconomic vulnerabilities. Tuberculosis diagnosis presents an opportunity for expanded health services to tuberculosis-affected households. We conducted a modified Delphi process to ascertain if and how expanded services should be offered to people with tuberculosis and their households. Purposively invited panellists were identified through professional networks and included researchers, service providers, policymakers and members of tuberculosis-affected communities. Panellists completed two online survey rounds. Round one sought to establish consensus on the perceived value of integration and capture diverse views on service integration priorities through free-text responses. Round two explored broad consensus statements (consensus defined as ≥75% agreement) developed from round one responses using Likert scales and country-specific priorities. Free-text responses were analysed using inductive thematic analysis. The percentage of panellists agreeing with each statement was calculated as a proportion of all responses, overall and by pre-specified subgroups of professional categories and WHO region. In round one, 223 panellists from 44 countries indicated strong support for expanded and better integrated services for people with tuberculosis (98% agreement), and their household contacts (84%). In round two, 324 people from 68 countries reached consensus on key motivations for service integration. These included improved tuberculosis treatment and other health outcomes among people with tuberculosis, and increased tuberculosis screening and preventive treatment uptake among contacts. Almost all (>99%) panellists agreed that people with tuberculosis should be routinely screened for relevant non-tuberculosis conditions, but only 69% thought this was appropriate among household contacts. There was consensus (93%) that population-wide tuberculosis screening should be integrated with other disease screening. Multiple, often context-specific, considerations for implementation were highlighted. Integrated tuberculosis screening and care is highly valued by global tuberculosis experts. This international consensus provides a strong mandate for research evaluating the feasibility and effectiveness of integrated tuberculosis service delivery and further policy and guideline development

Delphi · Delphi method · Health services · Likert scale · Service (business) · Thematic analysis · Tuberculosis · Delphi Technique in Research · Health Systems, Economic Evaluations, Quality of Life · Tuberculosis Research and Epidemiology

  • Defining consensus

    Open Access•Ivan R Diamond, Robert C Grant et al.•Journal of Clinical Epidemiology•2014

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    Open Access•Yohhei Hamada, Matteo Quartagno et al.•PLOS Global Public Health•2024

  • Integrated health checks as a person-centred approach to systematic screening of household tuberculosis contacts

    Open Access•Claire Jacqueline Calderwood, Edson Marambire et al.•PLOS Global Public Health•2025

  • Addressing TB multimorbidity in policy and practice

    Open Access•Alexander Jarde, Noemia Teixeira de Siqueira-Filha et al.•PLOS Global Public Health•2022

  • Optimizing the cascade of prevention to protect people from tuberculosis

    Open Access•Alberto Matteelli, Gavin Churchyard et al.•PLOS Global Public Health•2024

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