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From scarcity to sustainability

Policy pathways for equitable snakebite antivenom access in Africa

Bibliographic Data

ID19594532
AuthorsIni Umoh (0009-0002-5506-1612, Liverpool School of Tropical Medicine), Ezekiel Boro (0000-0002-1208-2985, Liverpool School of Tropical Medicine), Charles McLoughlin (0009-0005-4092-2039, Liverpool School of Tropical Medicine), Frank-Leonel Tianyi (0000-0001-5687-5285, Liverpool School of Tropical Medicine), George O Oluoch (0000-0001-9857-953X, Liverpool School of Tropical Medicine), Olawale Ajose, Daniel Irowa-Omoregie (Johns Hopkins University), Ian Burns (0000-0001-5351-5524, University of Liverpool), Ian Burn (University of Liverpool), Becky Jones-Phillips (0009-0000-2684-1180, Liverpool School of Tropical Medicine), Nicholas R Casewell (0000-0002-8035-4719, Liverpool School of Tropical Medicine)
EditorsStephen Olaide Aremu (0000-0002-7473-7254)
Year2026
Volume6
Issue5
Pagese0006490
Publication date2026-05-19
Open AccessYes
TypeARTICLE
VenuePLOS Global Public Health (JOURNAL)
Journal identifiersISSN: 2767-3375 • E-ISSN: 2767-3375
PublisherPublic Library of Science (PLoS) (PUBLISHER)
DOI10.1371/journal.pgph.0006490
PMID42154730
OpenAlexW7161749481
LanguageEN
References cited36

Snakebite envenoming (SBE) causes substantial mortality and long-term disability in sub-Saharan Africa (SSA), disproportionately affecting rural and economically vulnerable populations. Antivenom is currently the only approved snakebite therapy, yet chronic shortages, fragmented supply chains, high prices, and inconsistent product quality continue to undermine access, exacerbated further by persistent gaps in human resource capacity and health system infrastructure. This article synthesizes existing evidence on antivenom access barriers in SSA and shares feasible policy solutions with a health systems lens grounded in ongoing regional capacity strengthening efforts, World Health Organization (WHO) guidance, and market-shaping experience from other global health initiatives. Although there are multiple bottlenecks along the access continuum, the article focuses on three interlinked challenges: i) underinvested research capacity; ii) fragile and insufficient manufacturing capacity and iii) lack of sustainable financing. Emerging political commitments in countries like Kenya, coupled with expanding research and manufacturing capacity in the region, offer an opportunity to build a resilient regional ecosystem. Learnings from pooled procurement and blended finance in other therapeutic areas indicate potential pathways for stabilizing markets, reducing prices, and incentivizing sustainable production. Strengthening antivenom access in SSA therefore requires a coordinated policy approach anchored in regional research networks, regional manufacturing and blended finance, which collectively offer a viable route to reliable supply, improved affordability, and improved outcomes for tropical snakebite patients

Antivenom · Capacity building · Healthcare system · Procurement · Quality (philosophy) · Resource (disambiguation) · Scarcity · Healthcare and Venom Research · Rabies epidemiology and control · Venomous Animal Envenomation and Studies · Health Policy

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