The effect of biomass smoke exposure on quality-of-life among Ugandan patients treated for tuberculosis
A cross-sectional analysis
Bibliographic Data
| ID | 19594623 |
|---|---|
| Authors | Sophie Wennemann (0009-0008-7301-2295, Virginia Commonwealth University, corresponding author), Mudarshiru Bbuye (0000-0002-8635-2925, Makerere University), Stella Zawedde‐Muyanja (0000-0002-8823-7082, Makerere University), Trishul Siddharthan (0000-0001-9914-1839, University of Miami), Peter D Jackson (0000-0001-5108-9381, Virginia Commonwealth University) |
| Editors | Reginald Quansah (0000-0002-7318-4192) |
| Year | 2024 |
| Volume | 4 |
| Issue | 2 |
| Pages | e0002892 |
| Publication date | 2024-02-08 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | PLOS Global Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2767-3375 • E-ISSN: 2767-3375 |
| Publisher | Public Library of Science (PLoS) (PUBLISHER) |
| DOI | 10.1371/journal.pgph.0002892 |
| PMID | 38330053 |
| OpenAlex | W4391640745 |
| Language | EN |
| References cited | 19 |
More than half the global population burns biomass fuels for cooking and home heating, especially in low-middle income countries. This practice is a prominent source of indoor air pollution and has been linked to the development of a variety of cardiopulmonary diseases, including Tuberculosis (TB). The purpose of this cross-sectional study was to investigate the association between current biomass smoke exposure and self-reported quality of life scores in a cohort of previous TB patients in Uganda. We reviewed medical records from six TB clinics from 9/2019-9/2020 and conducted phone interviews to obtain information about biomass smoke exposure. A random sample of these patients were asked to complete three validated quality-of-life surveys including the St. Georges Respiratory Questionnaire (SGRQ), the EuroQol 5 Dimension 3 Level system (EQ-5D-3L) which includes the EuroQol Visual Analog Scale (EQ-VAS), and the Patient Health Questionnaire 9 (PHQ-9). The cohort was divided up into 3 levels based on years of smoke exposure–no-reported smoke exposure (0 years), light exposure (1–19 years), and heavy exposure (20+ years), and independent-samples-Kruskal-Wallis testing was performed with post-hoc pairwise comparison and the Bonferroni correction. The results of this testing indicated significant increases in survey scores for patients with current biomass exposure and a heavy smoke exposure history (20+ years) compared to no reported smoke exposure in the SGRQ activity scores (adj. p = 0.018) and EQ-5D-3L usual activity scores (adj. p = 0.002), indicating worse activity related symptoms. There was a decrease in EQ-VAS scores for heavy (adj. p = 0.007) and light (adj. p = 0.017) exposure groups compared to no reported exposure, indicating lower perceptions of overall health. These results may suggest worse outcomes or baseline health for TB patients exposed to biomass smoke at the time of treatment and recovery, however further research is needed to characterize the effect of indoor air pollution on TB treatment outcomes
Cohort · Cross-sectional study · Environmental health · Pathology · Physical therapy · Population · Smoke · Visual analogue scale · Air Quality and Health Impacts · Climate Change and Health Impacts · Energy and Environment Impacts · Medicine · Internal Medicine
EuroQol
Respiratory risks from household air pollution in low and middle income countries
Risk factors for disruptions in tuberculosis care in Uganda during the Covid-19 pandemic
Household Air Pollution Is Associated with Chronic Cough but Not Hemoptysis after Completion of Pulmonary Tuberculosis Treatment in Adults, Rural Eastern Democratic Republic of Congo
Assessing the Respiratory Effects of Air Pollution from Biomass Cookstoves on Pregnant Women in Rural India
| Highly cited | No |
|---|