The Case-Control Method

The case-control method, and to a lesser extent its case-based variants, have become a most important tool in the armamentarium of today's investigator of health problems. This book addresses a number of general and specific questions dealing with the case-control and other case-based methods, including how to design and implement a case-control study that minimizes biases; how to analyze the data to deal appropriately with confounding and to help identify interactions; how to interpret data from a case-control study; and how to use the method in a variety of problem solving situations. The book provides an exposition of the uses of a study of individual cases as well as case series in epidemiology. It describes the development of the comparative method as a basis for decision making in the health professions. The first part of the book deals with issues of design of the case control and other case based methods such as the case-crossover and case-cohort studies. In this section of the book several issues of design and analysis of case-control studies are presented within a framework for developing an information base for decision making in research and in health care. The second part of the book has a focus on the applications of the method. These include the use of case-control studies in outbreak investigations as well as other acute events such as disasters, the use of the method in health care and health services evaluation, and its use in genetic epidemiology as well as other applications

Confounding · Control (management) · Data science · Management science · Operations research · Statistics · Variety (cybernetics) · Artificial Intelligence · Computer Science · Engineering · Historical and modern epidemiology studies · HIV/AIDS Impact and Responses · Mathematics · Qualitative Comparative Analysis Research · Case-control method · Case-Control Studies · Epidemiologie · epidemiology · Fallstudie