Family history of cardiovascular disease and parental lifestyle behaviors are associated with offspring cardiovascular disease risk markers in childhood
Dados Bibliográficos
| AUTOR(ES) | |
|---|---|
| AFILIAÇÃO(ÕES) | State University of Londrina Brazil, Scientific Research Group Related to Physical Activity (GICRAF), Laboratory of Investigation in Exercise (LIVE), Department of Physical Education São Paulo State University (UNESP) Presidente Prudente Brazil, Bradford Institute for Health Research Bradford NHS Foundation Trust Bradford United Kingdom, Exercise and Health Laboratory Faculdade de Motrcidade Humana, Universidade de Lisboa Portugal, Department of Pathology Clinical and Toxicological Analysis, Center of Health Sciences, University Hospital, Londrina State University Londrina Brazil |
| ANO | Não informado |
| TIPO | Artigo |
| DOI | 10.1002/ajhb.22995 |
| ADICIONADO EM | 2025-08-18 |
Resumo
INTRODUCTIONCardiovascular disease risk markers have become more prevalent in childhood. To provide increased understanding of the etiology of this public health issue, we investigated associations between family characteristics with cardiovascular disease risk markers in adolescents from a developing nation.METHODSIn this cross‐sectional study data for fasting glucose, lipoproteins (LDL‐C and HDL‐C), triglycerides, and total cholesterol were collected from 991 adolescents aged 10–17 who were recruited from public schools in Londrina city, Southern Brazil. Family history of cardiovascular disease and parental engagement in risk behavior (alcohol consumption and tobacco smoking) were collected using a self‐reported parental questionnaire. Socioeconomic status, adolescent physical activity (estimated by Baecke questionnaire), self‐reported tobacco and alcohol intake, and somatic maturation (age at peak height velocity) were used as covariates. Logistic regression was used for the main analyses.RESULTSIndependent of adolescent lifestyle behaviors, associations (ORadj [95% CI]) were found between: (1) paternal family history of cardiovascular disease with increased likelihood of high adolescent offspring BMI (1.53 [1.01 to 2.32]) and high triglycerides (2.93 [1.04 to 8.27]); (2) maternal family history of cardiovascular disease with heightened odds of high adolescent offspring triglycerides (2.84 [1.02 to 7.91]); (3) maternal cardiovascular disease with higher odds of high fasting glucose (2.16 [1.13 to 4.14]), and (4) maternal smoking with increased odds of high LDL‐C (1.78 [1.14 to 2.79]) and high total cholesterol (1.77 [1.01 to 3.10]) in adolescent offspring.CONCLUSIONFamily history of cardiovascular disease and maternal tobacco smoking are related to increased cardiovascular risk in adolescents, potentially independent of their own lifestyle behaviors.