Instrumentation in X-ray crystallography
Past, present and future
Bibliographic Data
| ID | 20314973 |
|---|---|
| Authors | U W Arndt (MRC Laboratory of Molecular Biology, corresponding author) |
| Year | 2001 |
| Volume | 55 |
| Issue | 3 |
| Pages | 457-472 |
| Publication date | 2001-09-22 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Notes and Records the Royal Society Journal of the History of Science (JOURNAL) |
| Journal identifiers | ISSN: 0035-9149 • E-ISSN: 1743-0178 |
| Publisher | The Royal Society (PUBLISHER • GB) |
| DOI | 10.1098/rsnr.2001.0157 |
| OpenAlex | W1981898357 |
| Language | EN |
| Citations received | 2 |
This paper deals with the very great changes in X–ray crystallographic techniques and apparatus over a period of approximately the last 60 years. This is not a general history; it is a personal account of the developments with which I have been directly involved; it is, therefore, biased towards apparatus developments in the field of macromolecular crystallography in which I have worked during most of this period. The bias needs little excuse: many of the new techniques of X–ray crystallography were devised initially for large–molecule structure determinations which had most need of such advances in order to be feasible at all. Among them are the uses of computers in calculating electron density maps, the construction of automatic diffractometers and microdensitometers, the introduction of rotating-anode X–ray generators and of microfocus X–ray tubes, the development of electronic X–ray area detectors, the pioneering work on the use of synchrotron radiation for diffraction studies, the building of three–dimensional atomic models by computer and the complete automation of the mounting, selection and alignment of crystals on the diffractometer
Crystallography · Diffraction · Diffractometer · Engineering physics · Field (mathematics) · Instrumentation (computer programming) · Optics · Physics · Synchrotron radiation · Chemistry · Computer Science · Enzyme Structure and Function · History and advancements in chemistry · Mathematics · Various Chemistry Research Topics
| Citations per year | 0.08 |
|---|---|
| Citation span | 2002 - 2009 (8) |
| Highly cited | No |