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A Critique of Clinical Equipoise

Therapeutic Misconception in the Ethics of Clinical Trials

Datos Bibliográficos

ID20333368
AutoresFranklin G Miller (0000-0001-5942-1991), Howard Brody
Año2003
Volumen33
Número3
Páginas19
Fecha de publicación2003-05-01
Peer ReviewedSí
Open AccessNo
TipoARTICLE
RevistaThe Hastings Center Report (JOURNAL)
Identificadores de la revistaISSN: 0093-0334 • E-ISSN: 1552-146X
EditorialJSTOR (PUBLISHER)
DOI10.2307/3528434
PMID12854452
OpenAlexW2168550466
IdiomaFR
Citas recibidas45
Referencias citadas7

A predominant ethical view holds that physician-investigators should conduct their research with therapeutic intent. And since a physician offering a therapy wouldn't prescribe second-rate treatments, the experimental intervention and the best proven therapy should appear equally effective. "Clinical equipoise" is necessary. But this perspective is flawed. The ethics of research and of therapy are fundamentally different, and clinical equipoise should be abandoned

Clinical equipoise · Clinical trial · Engineering ethics · Intervention (counseling) · Perspective (graphical) · Psychiatry · Psychotherapist · Research ethics · Biomedical Ethics and Regulation · Ethics in Clinical Research · Ethics in medical practice · Medicine · Psychology

  • Determining Research through Underdetermined Treatment

    Open Access•Abraham Schwab•The AMA Journal of Ethic•2004

  • How Should a Research Ethicist Combat False Beliefs and Therapeutic Misconception Risk in Biomedical Research

    Open Access•Jennifer B Mccormick•The AMA Journal of Ethic•2018

  • The Question of Clinical Equipoise and Patients' Best Interests

    Open Access•Spencer Phillips Hey, Robert D Truog•The AMA Journal of Ethic•2015

  • Could Good Care Mean Withholding Information from Patients

    Open Access•Benjamin D Long, Andrew G Shuman•The AMA Journal of Ethic•2016

  • Race, Science and a Novel

    Open Access•Lawrence R Burns, LAWRENCE BURNS et al.•Developing World Bioethics•2008

  • Ethical complexities of screening for depression and intimate partner violence (IPV) in intervention studies

    Open Access•Victoria J Palmer, Jane Yelland et al.•BMC Public Health•2011

  • Daddy Issues

    Allison B Kavey•Literature and medicine•2018

  • Can Research and Care Be Ethically Integrated

    Open Access•Emily A Largent, Steven Joffe et al.•The Hastings Center Report•2011

  • The Elastic Ruler

    Open Access•Shane N Glackin•Philosophy of Science•2025

  • For the Common Good

    Alex John London•For the Common Good•2021

  • Placebo-Controlled Trials, Ethics of

    Open Access•Rieke van der Graaf, Annette Rid•International Encyclopedia of the…•2015

  • Communicating complex numeric information in clinical research

    Open Access•Barbara E Bierer, Sylvia Baedorf Kassis•Frontiers in Communication•2023

  • Equipoise and ethics in educational research

    Open Access•Leslie Burkholder•Theory and Research in Education•2021

  • The ethical anatomy of payment for research participants

    Open Access•Joanna Różyńska•Medicine Health Care and Philosophy•2022

  • Taking the principle of the primacy of the human being seriously

    Open Access•Joanna Różyńska•Medicine Health Care and Philosophy•2021

  • Understanding “interests”

    Open Access•Miriam Wiersma, Ian Kerridge et al.•Medicine Health Care and Philosophy•2025

  • What if all participants get the same treatment? An ethical perspective on single arm trials

    Chiara Mannelli, Giuseppe Traversa•Journal of Medical Ethics•2026

  • What role should equipoise play in experimental development economics

    Open Access•Marcos Picchio•Economics and Philosophy•2026

  • Developing Psychologically Compelling Understanding of the Involvement of Humans in Research

    Open Access•Kieran C O''Doherty, Martha Burge et al.•Human Arenas•2019

  • The Ethics of Health Care Delivery in a Pediatric Malaria Vaccine Trial

    Open Access•Claire Leonie Ward, David Shaw et al.•Journal of Empirical Research on…•2017

  • Perceptions of Equipoise, Risk–Benefit Ratios, and “Otherwise Healthy Volunteers” in the Context of Early-Phase HIV Cure Research in the United States

    Open Access•Karine Dubé, Lynda Dee et al.•Journal of Empirical Research on…•2017

  • Phase 3 Oncology Clinical Trials in South Africa

    Open Access•Tina Malan, Keymanthri Moodley•Journal of Empirical Research on…•2016

  • Effects of Participant Preferences in Unblinded Randomized Controlled Trials

    Open Access•Anna H L Floyd, Anne Moyer•Journal of Empirical Research on…•2010

  • Using the Emanuel et al. Framework to Assess Ethical Issues Raised by a Biomedical Research Ethics Committee in South Africa

    Open Access•Joyce Mahlako Tsoka-Gwegweni, Douglas Wassenaar•Journal of Empirical Research on…•2014

  • Extending experimentation

    Open Access•Alberto Cambrosio, P Keating et al.•New Genetics and Society•2018

  • Reflexivity and the clinician-researcher

    Open Access•Amy Hiller, Amy J Hiller et al.•Qualitative Research Journal•2016

  • Protecting People With Decisional Impairments and Legal Incapacity Against Biomedical Research Abuse

    Open Access•John H Noble, Vera Hassner Sharav•Journal of Disability Policy…•2008

  • Reevaluating the Ethical Issues in Porcine‐to‐Human Heart Xenotransplantation

    Open Access•H Silverman, Patrick N Odonkor et al.•The Hastings Center Report•2022

  • The Research-Clinical Practice Distinction, Learning Health Systems, and Relationships

    Open Access•Howard Brody, Franklin G Miller•The Hastings Center Report•2013

  • The Real‐World Ethics of Adaptive‐Design Clinical Trials

    Open Access•Laura E Bothwell, Aaron S Kesselheim•The Hastings Center Report•2017

  • Monitoring committees for research participant protection

    Open Access•Marcelo Nobile Franco, Beatriz Kaippert et al.•Revista Bioética•2022

  • Comitês de monitoramento para a proteção de participantes de pesquisa

    Open Access•Marcelo Nobile Franco, Beatriz Kaippert et al.•Revista Bioética•2022

  • Comités de seguimiento para la protección de los participantes en investigación

    Open Access•Marcelo Nobile Franco, Beatriz Kaippert et al.•Revista Bioética•2022

  • Research ethics in social sciences

    Débora Diniz•International Journal of Feminist…•2008

  • Wanted—egg donors for research

    Angela Ballantyne, Sheryl De Lacey•International Journal of Feminist…•2008

  • Recall and Appraisal of the Risks, Benefits, and Objectives of Interrupting HIV Treatment in an HIV Cure-Related Study

    Open Access•Anastasia Korolkova, Samuel Ndukwe et al.•AIDS and Behavior•2024

  • Engaging Diverse Social and Cultural Worlds

    Open Access•Olga Zvonareva, Nora Engel et al.•Developing World Bioethics•2015

  • Ética na pesquisa em ciências humanas

    Open Access•Débora Diniz•Ciência & Saúde Coletiva•2008

  • Usual and Unusual Care

    Kenneth E Freedland, David C Mohr et al.•Psychosomatic Medicine•2011

  • Justice and Fairness in the Kennedy Krieger Institute Lead Paint Study

    David Buchanan, David R Buchanan et al.•American Journal of Public Health•2006

  • Fairness in the Field

    Open Access•Margarita S Rayzberg, Margarita Rayzberg•Science Technology & Human Values•2019

  • Conflictos en ética de investigación con seres humanos

    Open Access•Miguel Kottow, Miguel H Kottow•Cadernos de Saude Publica•2005

  • International clinical trials, cardiovascular disease and treatment options in the Russian Federation

    Open Access•Olga Zvonareva, Nora Engel et al.•Social Science & Medicine•2015

  • Patients' perceptions of research in emergency settings

    Open Access•Neal W Dickert, Norman Ka et al.•Social Science & Medicine•2009

  • Configuring the patient as clinical research subject in the UK national health service

    Open Access•Mary Adams, Christopher Mckevitt•Anthropology and Medicine•2015

  • What's the Price of a Research Subject? Approaches to Payment for Research Participation

    Neal W Dickert, Neal Dickert et al.•New England Journal of Medicine•1999

  • What Makes Clinical Research Ethical?

    Ezekiel J Emanuel•JAMA•2000

  • Equipoise and the Ethics of Clinical Research

    Benjamin Freedman•New England Journal of Medicine•1987

  • Clarifying the Concepts of Research Ethics

    Robert J Levine•The Hastings Center Report•1979

  • False Hopes and Best Data

    Paul S Appelbaum, Peter Appelbaum et al.•The Hastings Center Report•1987

  • Leaving Therapy to Chance

    Don Marquis•The Hastings Center Report•1983

  • Placebo-Controlled Trials and the Logic of Clinical Purpose

    Benjamin Freedman•IRB Ethics and Human Research•1990

Obras citantes distintas45
Citas por año2,05
Intervalo de citas2004 - 2026 (23)
Velocidad de citacióncurrent
Altamente citadoNo
Tipos de citaNeutras: 36
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