Evaluation of Neolamarckia cadamba (Roxb.) bosser leaf extract on glucose tolerance in glucose-induced hyperglycemic mice
Bibliographic Data
| ID | 20345505 |
|---|---|
| Authors | Faiyaz Ahmed (0000-0002-7243-791X, University of Development Alternative), Shahnaz Rahman (0009-0003-1508-0373, University of Development Alternative, corresponding author), Nasir Ahmed (0000-0002-4863-0402, University of Development Alternative), Md Motaher Hossain (0000-0001-5667-7510, University of Development Alternative), M Hossain (0000-0003-0087-4018), Anup Biswas (0000-0002-6985-1247, University of Development Alternative), Shilpi Sarkar (0000-0001-9446-6925, University of Development Alternative), Hasanul Banna (0000-0002-6902-8525, University of Development Alternative), Amena Khatun (0000-0002-4986-6396, Lincoln University College) |
| Year | 2010 |
| Volume | 8 |
| Issue | 1 |
| Pages | 79-81 |
| Publication date | 2010-10-05 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | African Journal of Traditional Complementary and Alternative Medicines (JOURNAL) |
| Journal identifiers | ISSN: 0189-6016 • E-ISSN: 2505-0044 |
| Publisher | African Journals Online (AJOL) (PUBLISHER) |
| DOI | 10.4314/ajtcam.v8i1.60549 |
| PMID | 22238487 |
| OpenAlex | W1982974679 |
| Language | EN |
| Citations received | 4 |
| References cited | 3 |
Neolamarckia cadamba (Rubiaceae) leaf is used in folk medicine of Bangladesh for the treatment of diabetes, but so far no scientific study has been done which may support its use in traditional medicine. The present study was carried out to evaluate the possible glucose tolerance efficacy of methanolic extract of Neolamarckia cadamba leaf using glucose-induced hyperglycemic mice. The extract at different doses was administered one hour prior to glucose administration and blood glucose level was measured after two hours of glucose administration (p.o.) using glucose oxidase method. The statistical data indicated significant oral hypoglycemic activity on glucose-loaded mice at the two highest doses of 200 and 400 mg extract per kg body weight. Maximum anti-hyperglycemic activity was shown at 400 mg per kg body weight, which was comparable to that of, glibenclamide (10 mg/kg). The methanolic extract of leaf of Neolamarckia cadamba had beneficial effects in reducing the elevated blood glucose level of hyperglycemic mice
Body weight · Diabetes mellitus · Glibenclamide · Glucose oxidase · Traditional medicine · Bioactive natural compounds · Chemistry · Medicine · Natural Antidiabetic Agents Studies · Psidium guajava Extracts and Applications · Biochemistry · Endocrinology · Internal Medicine · Pharmacology
Traditional uses, phytochemistry and pharmacological properties of Neolamarckia cadamba
Antihyperglycemic Activities of Leaves of Three Edible Fruit Plants ( Averrhoa carambola, Ficus hispida and Syzygium samarangense ) of Bangladesh
Antihyperglycemic and antinociceptive activity evaluation of ‘Khoyer’ prepared from boiling the wood of Acacia catechu in water
Antihyperglycemic and antinociceptive activity evaluation of methanolic extract of whole plant of Amaranthus Tricolor L. (Amaranthaceae)
| Citations per year | 0.29 |
|---|---|
| Citation span | 2012 - 2016 (5) |
| Highly cited | No |