Anti-Inflammatory And Antimicrobial Activities Of Hippocratea indica Root Bark And Poga oleosa Fruits
Bibliographic Data
| ID | 20345923 |
|---|---|
| Authors | Omonike O Ogbole (0000-0002-6487-9494, Olabisi Onabanjo University), OO Ogbole, MN Ekor (Olabisi Onabanjo University), BB Oluremi (Olabisi Onabanjo University), EO Ajaiyeoba (University of Ibadan), AA Gbolade (Olabisi Onabanjo University, corresponding author), MA Ayoola, AA Adeyemi (Olabisi Onabanjo University) |
| Year | 2008 |
| Volume | 4 |
| Issue | 3 |
| Pages | 372 |
| Publication date | 2008-10-14 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | African Journal of Traditional Complementary and Alternative Medicines (JOURNAL) |
| Journal identifiers | ISSN: 0189-6016 • E-ISSN: 2505-0044 |
| Publisher | African Journals Online (AJOL) (PUBLISHER) |
| DOI | 10.4314/ajtcam.v4i3.31232 |
| PMID | 20161902 |
| OpenAlex | W2157656140 |
| Language | EN |
| References cited | 5 |
The methanolic extracts of Hippocratea indica root bark and Poga oleosa fruits were investigated for anti-inflammatory and antimicrobial activities. Both extracts inhibited carrageenan-induced paw oedema significantly in rats in a dose-dependent manner in 4 h. H. indica inhibited oedema significantly at the minimal dose (125 mg/ml, p< 0.05) from 2 h onward, and gave 100% inhibition in 4 h. at 250 mg/kg. It was shown to be a more potent anti-inflammatory agent than P. oleosa. Also, H. indica extract exhibited greater antimicrobial activity against tested bacteria, with Staphylococcus aureus being the most susceptible bacterium (MIC, 16 mg/ml). Both plants were inactive against Candida albicans. These results confirm the anti-inflammatory and antibacterial activities of the two plants. Keywords: Hippocratea indica, Poga oleosa, anti-inflammatory, antimicrobialAfrican Journal of Traditional and Complementary Medicine Vol. 4 (3) 2007: pp. 372-376
Anti-inflammatory · Antimicrobial · Bacteria · Biology · Candida albicans · Staphylococcus aureus · Traditional medicine · Chemistry · Medicine · Phytochemistry and biological activity of medicinal plants · Plant-Derived Bioactive Compounds · Sesquiterpenes and Asteraceae Studies · Horticulture · Microbiology · Pharmacology
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| Highly cited | No |
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