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A pilot study on the effect of Catha edulis frosk., (celastraceae) on metabolic syndrome in Wokw rats

Bibliographic Data

ID20345970
AuthorsSA Mahmood, S I Mahmood (University of Aden), U Lindequist (Universität Greifswald)
Year2008
Volume5
Issue3
Pages271-7
Publication date2008-10-20
Open AccessYes
TypeARTICLE
VenueAfrican Journal of Traditional Complementary and Alternative Medicines (JOURNAL)
Journal identifiersISSN: 0189-6016 • E-ISSN: 2505-0044
PublisherAfrican Journals Online (AJOL) (PUBLISHER)
DOI10.4314/ajtcam.v5i3.31283
PMID20161948
OpenAlexW2124993067
LanguageEN
Citations received3
References cited2

This study investigated the effect of Catha edulis (khat) on some important parameters of the metabolic syndrome in Wistar Ottawa Karlsburg W (WOKW) rat. The animals were fed with the standard chow containing 5% air dried pulverized khat leaves for 14 days; followed by the standard chow for 16 days. The khat leaves were sorted into green (khat light; KL) and crimson (khat dark; KD) leaves. The control rats were fed on standard chow. Blood glucose (G), serum insulin, serum leptin and serum lipids (triglycerides, total cholesterol, HDL-, LDL-, and VLDL cholesterol) were determined. Feeding with khat leaves reduced the body weight and the triglyceride level of the animals. The effect of KD on these parameters was stronger than that of KL. KD lowered the blood glucose concentration and the leptin content whereas KL was inactive. The khat intake had no significant influence on serum insulin, total serum cholesterol, HDL-, LDL- and VLDL-cholesterol

Biology · Botany · Celastraceae · Traditional medicine · Biochemical Analysis and Sensing Techniques · Medicine · Regulation of Appetite and Obesity · Sleep and Wakefulness Research

  • Khat (Catha edulis) upregulates lipolytic genes in white adipose tissue of male obese mice (C57BL/6J)

    Open Access•Mustafa Ahmed Alshagga, Zahurin Mohamed et al.•Journal of Ethnopharmacology•2020

  • Khat use and appetite

    Open Access•Andrine Lemieux, Andrine M Lemieux et al.•Journal of Ethnopharmacology•2015

  • Conflicting reports on the role of the glycemic effect of Catha edulis (Khat)

    Open Access•Abdulsamad Alsalahi, Mohammed A Alshawsh et al.•Journal of Ethnopharmacology•2016

  • Effect of Catha edulis on plasma glucose and C-peptide in both type 2 diabetics and non-diabetics

    Open Access•Riyadh Saif-Ali, A Al-Qirbi et al.•Journal of Ethnopharmacology•2003

  • Effect of Catha edulis (khat) chewing on plasma lipid peroxidation

    Open Access•Adel S Al-Zubairi, A Al-Zubairi et al.•Journal of Ethnopharmacology•2003

Citations per year0.27
Citation span2015 - 2020 (6)
Highly citedNo

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