In Vitro Anthelmintic Effect of Anogeissus Leiocarpus (Dc.) Guill. & Perr. Leaf Extracts and Fractions on Developmental Stages of Haemonchus Contortus
Dados Bibliográficos
| ID | 20346060 |
|---|---|
| Autores | J N Eloff (0000-0003-1494-9842, Onderstepoort Veterinary Academic Hospital), JN Eloff, IO Ademola, I T Ademola (University of Ibadan) |
| Ano | 2011 |
| Volume | 8 |
| Fascículo | 2 |
| Páginas | 134-9 |
| Data de publicação | 2011-01-17 |
| Peer Reviewed | Sim |
| Open Access | Sim |
| Tipo | ARTICLE |
| Periódico | African Journal of Traditional Complementary and Alternative Medicines (JOURNAL) |
| Identificadores do periódico | ISSN: 0189-6016 • E-ISSN: 2505-0044 |
| Editora | African Journals Online (AJOL) (PUBLISHER) |
| DOI | 10.4314/ajtcam.v8i2.63199 |
| PMID | 22238493 |
| OpenAlex | W2116677157 |
| Idioma | EN |
| Citações recebidas | 1 |
| Referências citadas | 3 |
The anthelmintic effect of acetone leaf extract and fractions of Anogeissus leiocarpus was investigated to determine the relative efficacy of the components as anthelmintic against Haemonchus contortus (Rudolphi). The fractions were obtained by solvent-solvent group separation of the leaf extract. The fractions were evaluated for ovicidal and larvicidal activity by egg hatch inhibition assay and larval development viability assay. Best-fit LC(50) values for egg hatch test were 0.360, 0.316, 0.093, 0.219 and 0.196 mg/ml for the crude acetone extract, hexane, chloroform, butanol, and 35% water in methanol fractions, respectively. While the best-fit LC(50) values for larval development and viability test were 0.509, 0.162, 0.186, 0.288 and 0.130 mg/ml for the crude acetone extract, hexane, chloroform, butanol, and 35% water in methanol fractions, respectively. The 35% water in methanol fractions was the more active on larvae, although differences in activity between fractions were not significant (p>0.05). A. leiocarpus leaf extracts could find application in anthelmintic therapy in veterinary practice
Acetone · Acute toxicity · Animal science · Anthelmintic · Biology · Botany · Butanol · Chloroform · Chromatography · Ethanol · Haemonchus contortus · Larva · Methanol · Solvent · Toxicity · Traditional medicine · Veterinary medicine · Botanical Research and Chemistry · Chemistry · Coccidia and coccidiosis research · Helminth infection and control · Medicine · Biochemistry · Ecology
| Obras citantes distintas | 1 |
|---|---|
| Citações por ano | 0,1 |
| Intervalo de citações | 2016 - 2016 (1) |
| Velocidade de citação | historical |
| Altamente citado | Não |