Study on anti-atherosclerotic effect of suxiao jiuxin pill and its mechanism

Bibliographic Data

ID20346419
AuthorsQX Guo (The Military General Hospital of Beijing PLA), Jiaxiang Zhang (0000-0002-8951-1469, The Military General Hospital of Beijing PLA), Y Q Li (0000-0001-6022-8013, The Military General Hospital of Beijing PLA), YQ Li, GF Zhang (The Military General Hospital of Beijing PLA)
Year2013
Volume11
Issue1
Pages97-102
Publication date2013-11-12
Open AccessYes
TypeARTICLE
VenueAfrican Journal of Traditional Complementary and Alternative Medicines (JOURNAL)
Journal identifiersISSN: 0189-6016 • E-ISSN: 2505-0044
PublisherAfrican Journals Online (AJOL) (PUBLISHER)
DOI10.4314/ajtcam.v11i1.14
PMID24653560
OpenAlexW1977231514
LanguageEN
Citations received2
References cited1

BACKGROUND: Suxiao Jiuxin Pill is composed of Ligusticum wallichii, Borneolum Syntheticum and other drugs; it has qi promoting and blood circulation activating, meridian dredging and pain relieving efficacies. The objective of this paper is to study the effect of Suxiao Jiuxin Pill (quick-acting heart reliever), in atherosclerosis (AS) rat model and explore the mechanism for its prevention and treatment of AS. MATERIALS AND METHODS: AS rat model was established by high cholesterol diet and single intra-peritoneal injection of increased dose of vitamin D3. RESULTS: Compared with the model group, Suxiao Jiuxin Pill medium-and high-dose groups and atorvastatin group can effectively regulate lipid metabolism. CONCLUSION: We conclude that Suxiao Jiuxin Pill has a good hypo-lipidemic effect, and can inhibit the occurrence and development of AS

Atorvastatin · Pill · Traditional medicine · Andrographolide Research and Applications · Ginger and Zingiberaceae research · Medicine · Traditional Chinese Medicine Analysis · Internal Medicine · Pharmacology

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