Dramatic founder effects in Amerindian mitochondrial DNAs

Dados Bibliográficos

AUTOR(ES) William C. Knowler , Douglas C. Wallace , Katherine Garrison
ANO 1985
TIPO Artigo
PERIÓDICO American Journal of Physical Anthropology
ISSN 0002-9483
E-ISSN 1096-8644
EDITORA Berghahn Journals (United Kingdom)
DOI 10.1002/ajpa.1330680202
CITAÇÕES 30
ADICIONADO EM 2025-08-18
MD5 b5195e4b7f7bac4d73a30ab8ded19470

Resumo

Southwestern American Indian (Amerindian) mitochondrial DNAs (mtDNAs) were analyzed with restriction endonucleases and found to contain Asian restriction fragment length polymorphisms (RFLPs) but at frequencies very different from those found in Asia. One rare Asian HincII RFLP was found in 40% of the Amerindians. Several mtDNAs were discovered which have not yet been observed on other continents and different tribes were found to have distinctive mtDNAs. Since the mtDNA is inherited exclusively through the maternal lineage, these results suggest that Amerindian tribes were founded by small numbers of female lineages and that new mutations have been fixed in these lineages since their separation from Asia.

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Ferramentas

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