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Sex-specific patterns and differences in dementia and Alzheimer’s disease using informatics approaches

Bibliographic Data

ID20393334
AuthorsJay G Ronquillo (0000-0002-0438-7172, corresponding author), Merritt Rachel Baer, William Lester (0000-0003-4086-9280, Harvard University), William T Lester
Year2016
Volume28
Issue5
Pages403-411
Publication date2016-09-02
Open AccessNo
TypeARTICLE
VenueJournal of Women & Aging (JOURNAL)
Journal identifiersISSN: 0895-2841 • E-ISSN: 1540-7322
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/08952841.2015.1018038
PMID27105335
OpenAlexW2338471433
LanguageEN
Citations received1
References cited25

The National Institutes of Health Office of Research on Women's Health recently highlighted the critical need for explicitly addressing sex differences in biomedical research, including Alzheimer's disease and dementia. The purpose of our study was to perform a sex-stratified analysis of cognitive impairment using diverse medical, clinical, and genetic factors of unprecedented scale and scope by applying informatics approaches to three large Alzheimer's databases. Analyses suggested females were 1.5 times more likely than males to have a documented diagnosis of probable Alzheimer's disease, and several other factors fell along sex-specific lines and were possibly associated with severity of cognitive impairment

Alzheimer's disease · Cognition · Cognitive impairment · Dementia · Disease · Informatics · Pathology · Psychiatry · Clinical Psychology · Cognitive Abilities and Testing · Computer Science · Dementia and Cognitive Impairment Research · Medicine · Psychology · Sex and Gender in Healthcare · Gerontology

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Citations per year0.17
Citation span2020 - 2020 (1)
Highly citedNo

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