The population genetics of quechuas, the largest native south american group: Autosomal sequences, SNPs, and microsatellites evidence high level of diversity
Dados Bibliográficos
| AUTOR(ES) | |
|---|---|
| ANO | 2012 |
| TIPO | Artigo |
| PERIÓDICO | American Journal of Physical Anthropology |
| ISSN | 0002-9483 |
| E-ISSN | 1096-8644 |
| EDITORA | Berghahn Journals (United Kingdom) |
| DOI | 10.1002/ajpa.22013 |
| CITAÇÕES | 1 |
| ADICIONADO EM | 2025-08-18 |
| MD5 |
bd63080a5f4b30445e47acf23a466920
|
Resumo
Elucidating the pattern of genetic diversity for non‐European populations is necessary to make the benefits of human genetics research available to individuals from these groups. In the era of large human genomic initiatives, Native American populations have been neglected, in particular, the Quechua, the largest South Amerindian group settled along the Andes. We characterized the genetic diversity of a Quechua population in a global setting, using autosomal noncoding sequences (nine unlinked loci for a total of 16 kb), 351 unlinked SNPs and 678 microsatellites and tested predictions of the model of the evolution of Native Americans proposed by (Tarazona‐Santos et al.: Am J Hum Genet 68 (2001) 1485–1496). European admixture is ) 1485–1496), proposed based on Y‐chromosome data, which predicts high genomic diversity due to the high level of gene flow between Andean populations and their long‐term effective population size. Am J Phys Anthropol 2012. © 2012 Wiley Periodicals, Inc.