Effects of Salvia officinalis L. and Chamaemelum nobile (L.) extracts on inflammatory responses in two models of human cells
Primary subcutaneous adipocytes and neuroblastoma cell line (SK-N-SH)
Bibliographic Data
| ID | 21095252 |
|---|---|
| Authors | Carla Russo (0000-0002-8356-7138, University of Buckingham), Kieron D Edwards (0000-0002-7202-4082), Gemma Margetts (0000-0002-9020-1695, University of Buckingham), Sotirios Kleidonas, Nawel S Zaibi (0000-0001-6996-2687, European Genomic Institute for Diabetes), John C Clapham (0000-0002-6995-8642, University of Buckingham), Mohamed S Zaibi (0000-0001-9667-8091, University of Buckingham, corresponding author) |
| Year | 2021 |
| Volume | 268 |
| Pages | 113614 |
| Publication date | 2021-03-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2020.113614 |
| PMID | 33246119 |
| OpenAlex | W3107773231 |
| Language | EN |
| References cited | 43 |
Sage decreased the pro-inflammatory markers mostly in human adipocytes, whereas chamomile showed a strong reduction in both cell populations. Both extracts reduced the ACM-induced inflammation effect and might be used as a preventive treatment for late-life cognitive impairment related to low-grade chronic inflammation associated with obesity. Further studies are needed to investigate their combination on other chronic inflammation-related diseases such as type 2 diabetes or rheumatoid arthritis
Biological activity · Biology · Cell culture · In vitro · Neuroblastoma · Officinalis · Pharmacognosy · Salvia officinalis · Traditional medicine · Adipokines, Inflammation, and Metabolic Diseases · Atherosclerosis and Cardiovascular Diseases · Medicine · Neuroinflammation and Neurodegeneration Mechanisms · Biochemistry · Pharmacology
| Highly cited | No |
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