Haematological Properties of Aqueous Extracts of Phyllantus amarus (Schum and Thonn.) and Xylopia aethiopica (Dunal) A. Rich in Albino Rats

Bibliographic Data

ID21118337
AuthorsIdowu A Taiwo (University of Lagos, corresponding author), Bola O Oboh (University of Lagos), Bola Oboh (0000-0002-4938-352X, University of Lagos), Peniel N Francis-Garuba (University of Lagos)
Year2009
Volume3
Issue2
Pages99-103
Publication date2009-07-01
Open AccessYes
TypeARTICLE
VenueStudies on Ethno-Medicine (JOURNAL)
Journal identifiersISSN: 0973-5070 • E-ISSN: 2456-6772
PublisherKamla Raj Enterprises (PUBLISHER)
DOI10.1080/09735070.2009.11886345
OpenAlexW2144485032
LanguageEN
Citations received1

A study on haematological effects of aqueous extracts from Phyllantus amarusand Xylopia aethiopica was investigated in albino rats. The extracts from both plants caused a dose-dependent decrease in erythrocyte sedimentation rate (ESR) with 400mg/kg of X. aethiopicacausing the least ESR of 2.7±0.6mm/hr. Significant increases were obtained in red blood cell (RBC) count especially with 100mg/kg of P. amarusand X. aethiopicathat caused 5.6% and 7.8% increases in RBC count respectively (P 0.05).Total and differential count studies showed significant increases in the number of circulating leucocytes and neutrophils respectively especially with 100mg/kg of extracts (P<0.05). Assessment of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) gave significantly higher values of ALT for P. amarus – treated rats (P < 0.05). It was therefore suggested that while both plants can serve as immune boosters and blood tonics, there is need for caution on excessive and prolonged consumption of P. amarus

Annonaceae · Aqueous extract · Biology · Traditional medicine · Medicine · Moringa oleifera research and applications · Pharmacological Effects of Natural Compounds · Phytochemistry and Bioactivity Studies

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