Reaching Out to Adolescents at High Risk of HIV Infection in Brazil

Demand Creation Strategies for PrEP and Other HIV Combination Prevention Methods

Bibliographic Data

ID21292187
AuthorsLaio Magno (0000-0003-3752-0782, Universidade Federal da Bahia, corresponding author), Fabiane Soares Gomes (0000-0003-4067-7860, Universidade Federal da Bahia), Eliana Miura Zucchi (0000-0001-6234-1490, Universidade Católica de Santos), Marcos Eustórgio (Universidade Federal da Bahia), Alexandre Grangeiro (0000-0001-5157-0597, Universidade de São Paulo), Dulce Ferraz (Fundação Oswaldo Cruz), Dirceu Bartolomeu Greco (0000-0002-4419-5634, Universidade Federal de Minas Gerais), Maria Mercedes Loureiro Escuder (0000-0002-3103-2617), Ines Dourado (0000-0003-1675-2146, Universidade Federal da Bahia)
Year2023
Volume52
Issue2
Pages703-719
Publication date2023-02-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueArchives of Sexual Behavior (JOURNAL)
Journal identifiersISSN: 0004-0002 • E-ISSN: 1573-2800
PublisherSpringer Science and Business Media LLC (PUBLISHER)
DOI10.1007/s10508-022-02371-y
PMID35876978
OpenAlexW4287447398
LanguageEN
Citations received13
References cited50

Using baseline data from the PrEP1519 cohort, in this article we aimed to analyze: (i) the effectiveness of demand creation strategies (DCS) to enroll adolescent men who have sex with men (AMSM) and adolescent transgender women (ATGW) into an HIV combination prevention study in Brazil; (ii) the predictors of DCS for adolescents’ enrollment; and (iii) the factors associated with DCS by comparing online and face-to-face strategies for enrollment. The DCS included peer recruitment (i.e., online and face-to-face) and referrals from health services and non-governmental organizations (NGOs). AMSM and ATGW who agreed to participate in the study could opt to enroll in either PrEP (PrEP arm) or to use other prevention methods (non-PrEP arm). Bivariate and multivariate analyses were conducted and logistic regression odds ratios were estimated. The DCS reached 4529 AMSM and ATGW, the majority of which were derived online (73.8%). Of this total, 935 (20.6%) enrolled to participate (76.6% in PrEP arm and 23.4% in non-PrEP arm). The effectiveness of enrolling adolescents into both arms was greater via direct referrals (235/382 and 84/382, respectively) and face-to-face peer recruitment (139/670 and 35/670, respectively) than online (328/3342). We found that a combination under DCS was required for successful enrollment in PrEP, with online strategies majorly tending to enroll adolescents of a higher socioeconomic status. Our findings reinforce the need for DCS that actively reaches out to all adolescents at the greatest risk for HIV infection, irrespective of their socioeconomic status

Cohort · Environmental health · Face-to-face · Family medicine · Human immunodeficiency virus (HIV) · Logistic regression · Men who have sex with men · Multivariate analysis · Odds · Odds ratio · Peer group · Population · Public health · Socioeconomic status · Young adult · Adolescent Sexual and Reproductive Health · Demography · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Internal Medicine · Medicine · Nursing · Psychology · Social Psychology · Gerontology

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