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The Republic of Translational Medicine

Bibliographic Data

ID21300070
AuthorsJohnathon Liddicoat (King's College London, corresponding author), James Parish (King’s Information and Intellectual Property Hub, King’s College London), Mateo Aboy (0000-0002-5168-4321, University of Cambridge)
Year2026
Pages1-26
Publication date2026-06-16
Open AccessYes
TypeARTICLE
VenueThe Cambridge Law Journal (JOURNAL)
Journal identifiersISSN: 0008-1973 • E-ISSN: 1469-2139
PublisherCambridge University Press (CUP) (PUBLISHER)
DOI10.1017/s0008197326101469
OpenAlexW7164887929
LanguageEN

Established pharmaceutical innovation theory holds that companies and patents are essential for developing new treatments. Yet, it does not adequately explain numerous clinical trials conducted by hospitals and universities. This paper introduces a new, complementary theory that describes a parallel system of innovation, focused on new uses of already authorised drugs, particularly once generics are available. These trials are driven by incentives previously associated with “open science” and “user innovation” rather than by patents and cost 90 per cent less than commercial equivalents. This “hidden” research system could regularly provide society with affordable treatments

Alternative medicine · Clinical trial · Incentive · The Republic · Translational medicine · Translational research · Biomedical Ethics and Regulation · Pharmaceutical Economics and Policy · Pharmaceutical industry and healthcare

Highly citedNo

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