Developmental Language Disorder and Psychopathology
Disentangling Shared Genetic and Environmental Influences
Bibliographic Data
| ID | 21350063 |
|---|---|
| Authors | Umar Toseeb (0000-0002-7536-2722, University of York, corresponding author), Olakunle A Oginni (0000-0002-2340-9429, King's College London), Philip S Dale (0000-0002-7697-8510, The University of New Mexico, Albuquerque, USA) |
| Year | 2022 |
| Volume | 55 |
| Issue | 3 |
| Pages | 185-199 |
| Publication date | 2022-05-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Learning Disabilities (JOURNAL) |
| Journal identifiers | ISSN: 0022-2194 • E-ISSN: 1538-4780 |
| Publisher | SAGE Publications (PUBLISHER • US) |
| DOI | 10.1177/00222194211019961 |
| PMID | 34112015 |
| OpenAlex | W3160895003 |
| Language | EN |
| Citations received | 2 |
| References cited | 70 |
There is considerable variability in the extent to which young people with developmental language disorder (DLD) experience mental health difficulties. What drives these individual differences remains unclear. In the current article, data from the Twin Early Development Study were used to investigate the genetic and environmental influences on psychopathology in children and adolescents with DLD ( n = 325) and those without DLD ( n = 865). Trivariate models were fitted to investigate etiological influences on DLD and psychopathology, and bivariate heterogeneity and homogeneity models were fitted and compared to investigate quantitative differences in etiological influences on psychopathology between those with and without DLD. The genetic correlation between DLD and internalizing problems in childhood was significant, suggesting that their co-occurrence is due to common genetic influences. Similar, but nonsignificant effects were observed for externalizing problems. In addition, genetic influences on internalizing problems, but not externalizing problems, appeared to be higher in young people with DLD than those without DLD, suggesting that the presence of DLD may exacerbate genetic risk for internalizing problems. These findings indicate that genetic influences on internalizing problems may also confer susceptibility to DLD (or vice versa) and that DLD serves as an additional risk factor for those with a genetic predisposition for internalizing problems
Bivariate analysis · Child psychopathology · Developmental psychology · Developmental psychopathology · Genetic predisposition · Heritability · Psychopathology · Twin study · Child Development and Digital Technology · Clinical Psychology · Genetics · Language Development and Disorders · Psychology · Reading and Literacy Development
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| Citations per year | 1 |
|---|---|
| Citation span | 2024 - 2025 (2) |
| Highly cited | No |