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Cognitive behavioral therapy (CBT) plus attention bias modification (ABM) reduces anxiety sensitivity and depressive symptoms in panic disorder

A pilot randomized trial

Bibliographic Data

ID21392130
AuthorsNur Hani Zainal (0000-0002-2023-3173, Department of Healthcare Policy Harvard Medical School Boston MA USA, corresponding author), Samantha N Hellberg (0000-0002-0302-2382, Department of Psychology University of North Carolina at Chapel Hill Chapel Hill NC USA), Katherine E Kabel (0000-0002-1803-874X, Department of Psychiatry Harvard Medical School, Massachusetts General Hospital Boston MA USA), Claire M Hotchkin (0000-0002-3182-8527, Department of Psychiatry Harvard Medical School, Massachusetts General Hospital Boston MA USA), Amanda W Baker (0000-0002-0103-5411, Department of Psychiatry Harvard Medical School, Massachusetts General Hospital Boston MA USA)
Year2023
Volume64
Issue4
Pages390-400
Publication date2023-08-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueScandinavian Journal of Psychology (JOURNAL)
Journal identifiersISSN: 0036-5564 • E-ISSN: 1467-9450
PublisherWiley (PUBLISHER • GB)
DOI10.1111/sjop.12902
PMID36707979
OpenAlexW4318320708
LanguageEN
References cited75

BACKGROUND: Cognitive bias theories propose that reducing threat hypervigilance in mental disorders can augment cognitive behavioral therapy (CBT) outcomes. However, no studies have tested whether adding attention bias modification (ABM) can effectively enhance CBT's effects on anxiety sensitivity (AS), electromyography (EMG), and skin conductance (SC) for panic disorder (PD). This pilot randomized controlled trial (RCT) thus aimed to evaluate the efficacy of CBT + ABM (vs. CBT plus attention training placebo; PBO) on those outcomes. METHOD: This study is a secondary analysis (Baker et al., 2020). Adults with PD were randomized to receive CBT + ABM (n = 11) or CBT + PBO (n = 12). Before each of the first five CBT sessions, CBT + ABM and CBT + PBO participants completed a 15-min ABM task or attention training PBO, respectively. AS and depression severity as well as SC and EMG during habituation to a loud-tone startle paradigm were assessed. Hierarchical Bayesian analyses were conducted. RESULTS: During pre-post-treatment and pre-follow-up, CBM + ABM (vs. CBT + PBO) led to a notably greater reduction in ASI-Physical (between-group d = -1.26 to -1.25), ASI-Cognitive (d = -1.16 to -1.10), and depression severity (d = -1.23 to -0.99). However, no between-group difference was observed for ASI-Social, EMG, or SC indices. DISCUSSION: Adding a brief computerized ABM intervention to CBT for PD protocols may enhance therapeutic change

Anxiety · Anxiety sensitivity · Attentional bias · Cognition · Cognitive behavioral therapy · Cognitive therapy · Habituation · Hypervigilance · Panic disorder · Psychiatry · Psychotherapist · Randomized controlled trial · Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes · Clinical Psychology · Medicine · Mental Health Research Topics · Psychology · Treatment of Major Depression

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