The Protective Role of Intestinal Microbiota in Colorectal Cancer Treatment

A Scoping Review

Bibliographic Data

ID21433705
AuthorsJéssica Rosa Thiesen Cunha (0000-0002-4305-8259, Hospital de Clínicas de Porto Alegre), Elissandra Maria Faiz (0000-0003-0530-0603, Universidade Federal do Rio Grande do Sul), Elizete Maria de Souza Bueno (0000-0003-0352-7679, Hospital de Clínicas de Porto Alegre), Eliana Rosa Da Fonseca (0000-0003-4753-1864, Universidade Federal do Rio de Janeiro), Thaís Ortiz Hammes (0000-0001-8010-3840, Hospital de Clínicas de Porto Alegre), Adriana Serdotte Freitas Cardoso (0000-0002-5148-8531, Hospital de Clínicas de Porto Alegre), Letícia Becker Vieira (0000-0001-5850-7814, Universidade Federal do Rio Grande do Sul), Isabel Cristina Echer (0000-0001-5425-205X, Universidade Federal do Rio Grande do Sul)
Year2024
Volume33
Publication date2024-01-01
Open AccessYes
TypeARTICLE
VenueTexto & Contexto - Enfermagem (JOURNAL)
Journal identifiersISSN: 0104-0707 • E-ISSN: 1980-265X
PublisherFapUNIFESP (SciELO) (PUBLISHER)
DOI10.1590/1980-265x-tce-2024-0109en
OpenAlexW4406244285
LanguageEN
References cited31

Objective: to map protective factors related to the intestinal microbiota (IM) of patients with colorectal cancer undergoing intravenous chemotherapy treatment. Method: this is a scoping review in accordance with the JBI recommendations and reported, according to the PRISMA-ScR checklist, to answer the research question: what are the protective factors for the IM of adult patients with colorectal cancer undergoing intravenous chemotherapy treatment? Data collection was carried out from January to June 2023, in the WPRIM, LILACS, IBECS, BINACIS from the VHL Portal, MEDLINE/PubMed, Embase and Scopus, Web of Science/Elsevier, Cochrane Library, CINAHL, Academic Search Premier, Food Science Source and Food Science and Technology Abstracts/EBSCO, Google Scholar and the CAPES Theses & Dissertations Catalog databases, without time or language filter. Selection was carried out by two reviewers, and any disagreements were assessed by a third party. Data extraction was performed using an instrument developed by the authors after a pilot test. The protocol registered in the Open Science Framework: OSF.IO/Y2U6V. Results: a total of 3,025 documents were mapped during the study period. The analyses included 30 articles published between 2007 and 2023. The research reiterates the correlation of dysbiosis with the emergence of colorectal tumors and IM modulation by interventions with the reduction of side effects of chemotherapy and increased quality of life. Conclusion: the use of probiotics, yogurts and omega 3 have been shown to be protective, safe and effective in altering IM composition, reducing the side effects of chemotherapy. However, further studies are needed to determine the relationship between IM and treatment effectiveness

Cancer · Checklist · CINAHL · Cochrane Library · Colorectal cancer · Data extraction · Intensive care medicine · MEDLINE · Oxaliplatin · Psychological intervention · Randomized controlled trial · Scopus · Cancer survivorship and care · Gut microbiota and health · Internal Medicine · Medicine · Nursing · Oral health in cancer treatment · Psychology

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