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Dietary Inflammatory Index and the Risk of Frailty Among Older Adults

A Systematic Review and Meta-Analysis

Bibliographic Data

ID21460741
AuthorsSajjad Moradi (0000-0003-0108-187X, Isfahan University of Medical Sciences), Amir Hadi (0000-0001-9952-6579, Halal Research Center of IRI, FDA, Tehran, Iran), Hamed Mohammadi (Isfahan University of Medical Sciences), Omid Asbaghi (Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran), Mehdi Zobeiri (Kermanshah University of Medical Sciences), Wolfgang Marx (0000-0002-0576-6713, School of Medicine, Barwon Health, IMPACT (the Institute for Mental and Physical Health and ClinicalTranslation), Food & Mood Centre, Deakin University, Melbourne, Victoria, Australia), Mohammad Hassan Entezari (Isfahan University of Medical Sciences)
Year2021
Volume43
Issue7-8
Pages323-331
Publication date2021-08-01
Open AccessYes
TypeARTICLE
VenueResearch on Aging (JOURNAL)
Journal identifiersISSN: 0164-0275 • E-ISSN: 1552-7573
PublisherSAGE Publications (PUBLISHER • US)
DOI10.1177/0164027520948176
LanguageEN
References cited42

A systematic review and meta-analysis was conducted to comprehensively examine the association between Dietary Inflammatory Index (DII®) score and risk of frailty. Frailty risk were available from five studies comprising 13,908 older adults. Furthermore, frailty related parameters were extacted from two studies with 7,539 individuals. A pooled adjusted odds ratio analysis indicated that there was an association between DII® score and frailty risk (OR = 1.24, 95%CI: 1.6–1.33, P 2 = 0.0%). The results of frailty related parameters demonstrated that DII® score was associated with weakness risk (OR = 1.12, 95%CI: 1.05–1.19, P = 0.014, I 2 = 0.0%), but not other frailty-related parameters including exhaustion, low BMI or low physical activity. The results of this meta-analysis suggest that older adults who exhibit higher DII® scores have an increased frailty risk. Further prospective cohort studies with longer follow-up periods, are needed to support this possible association between DII® score and frailty risk

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