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Childhood Stress, Loneliness, and Cardiovascular Diseases in Later Life

Does Family Support or Friend Support Matter

Bibliographic Data

ID21460973
AuthorsJia-Jia Zhou (0000-0001-5677-9015, Hong Kong Baptist University, corresponding author), Youjuan Zhang (Hong Kong Polytechnic University), Xue Bai (0000-0002-0502-7291, Hong Kong Polytechnic University)
Year2026
Pages1640275261438709-1640275261438709
Publication date2026-03-24
Open AccessYes
TypeARTICLE
VenueResearch on Aging (JOURNAL)
Journal identifiersISSN: 0164-0275 • E-ISSN: 1552-7573
PublisherSAGE Publications (PUBLISHER • US)
DOI10.1177/01640275261438709
PMID41873647
OpenAlexW7140193256
LanguageEN
References cited57

This study investigates the associations between distinct childhood stressors (i.e., health threats, financial hardship, and interpersonal trauma) and cardiovascular diseases (CVD) in later life, with a focus on loneliness as a mediator and the moderating roles of family and friend support. Cross-sectional data were used in this study, including 5,007 Hong Kong residents aged 50 and above. CVD was assessed via self-reported diagnoses of heart diseases or stroke. All three childhood stressors were associated with increased CVD risk in old age, with loneliness significantly mediating these associations. Friend support consistently buffered the effects of all stressors on loneliness, whereas family support was protective only in case of financial hardship. These findings advance understanding of the psychological pathways connecting childhood stress to CVD. It highlights that the efficacy of social support varies based on the type of social relationship and stressor domain, rather than serving as a generic buffer

Cardiovascular health · Family support · Interpersonal communication · Interpersonal relationship · Loneliness · Social support · Stressor · Cardiac Health and Mental Health · Health disparities and outcomes · Stress Responses and Cortisol

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