Risk Dilution
Or, How to Run a Minimal‐Risk HIV Challenge Trial
Bibliographic Data
| ID | 21497617 |
|---|---|
| Authors | Robert Steel (0000-0003-4879-2070, University of Nebraska Omaha NE USA, corresponding author) |
| Year | 2023 |
| Volume | 40 |
| Issue | 1 |
| Pages | 133-149 |
| Publication date | 2023-02-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Applied Philosophy (JOURNAL) |
| Journal identifiers | ISSN: 0264-3758 • E-ISSN: 1468-5930 |
| Publisher | Wiley (PUBLISHER • GB) |
| DOI | 10.1111/japp.12617 |
| OpenAlex | W4294415449 |
| Language | EN |
| Citations received | 2 |
Bioethicists broadly agree that there is a limit to the level of net risk that biomedical research may permissibly impose on participants, even in cases where the potential of that research to improve the health of the population health would be great. Although some may permissibly volunteer to take on some degree of pro‐social risk, no one, not even a willing volunteer, may ever be outright sacrificed for others. One might think this perspective, if correct, makes it effectively impossible to study interventions with high intrinsic risks. But I describe a method – risk dilution – by which an extremely high‐risk intervention can nonetheless be effectively studied in the context of an acceptably low‐risk trial. I then defend risk dilution from objections
Actuarial science · Business · Environmental health · Family medicine · Population · Psychiatry · Psychological intervention · Social risk · Volunteer · Computer Science · Ethics in Clinical Research · Ethics in medical practice · Health Systems, Economic Evaluations, Quality of Life · Medicine · Psychology
| Unique citing works | 2 |
|---|---|
| Citations per year | 1 |
| Citation span | 2024 - 2026 (3) |
| Citation velocity | current |
| Highly cited | No |
| Citation types | Neutral: 2 |