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Toward a Global Bioethics

Principlism and the Problem of Political Legitimacy

Bibliographic Data

ID21504263
AuthorsMarco Annoni (0000-0003-3259-1856, National Research Council of Italy (CNR) Interdepartmental Center for Research Ethics and Integrity (CID‐Ethics) Rome Italy, corresponding author)
Year2026
Volume40
Issue1
Pages5-11
Publication date2026-01-01
Open AccessYes
TypeARTICLE
VenueBioethics (JOURNAL)
Journal identifiersISSN: 0269-9702 • E-ISSN: 1467-8519
PublisherWiley (PUBLISHER • GB)
DOI10.1111/bioe.13434
PMID40483723
OpenAlexW4411126900
LanguageEN
References cited6

Tom Beauchamp and James Childress's Principles of Biomedical Ethics introduced principlism—or the “four principles approach”—which has since become one of the most influential frameworks in contemporary bioethics. However, its potential to serve as a foundation for shared transcultural bioethical norms has elicited both substantial support and considerable critique. In this article, I analyze two notable attempts that utilize, or appear to be modeled after, principlism as a basis for global bioethics: Beauchamp and Childress's original formulation and the recently revised International Code of Medical Ethics by the World Medical Association. I argue that each model fails, but for different reasons. Beauchamp and Childress's account is rooted in particular moralities, making it suitable for guiding action in specific clinical contexts but ill‐equipped to handle global ethical pluralism. Conversely, the WMA's approach is deficient due to its undefined moral foundation and lack of political legitimacy. To address these shortcomings, I outline a third approach designed to make explicit the connection between principlism, global bioethics, and the problem of political legitimacy

Bioethics · Engineering ethics · Environmental ethics · Epistemology · Legitimacy · Political science · Politics · Sociology · Biomedical Ethics and Regulation · Ethics in medical practice · Law · Patient Dignity and Privacy · Philosophy

  • Critique of Pure Reason

    Open Access•Immanuel Kant, Paul Guyer et al.•Critique of Pure Reason•1998

  • The revised International Code of Medical Ethics

    Ramin W Parsa-Parsi, Raanan Gillon et al.•Journal of Medical Ethics•2024

Highly citedNo

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