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Part 6

The P blood group system: Genetic adaptation to helminthic zoonoses

Bibliographic Data

ID2150788
AuthorsJohn Blangero (0000-0001-6250-5723, Case Western Reserve University, corresponding author)
Year1982
Volume6
Issue1
Pages57-69
Publication date1982-01-01
Open AccessNo
TypeARTICLE
VenueMedical Anthropology (JOURNAL)
Journal identifiersISSN: 0145-9740 • E-ISSN: 1545-5882
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/01459740.1982.9987006
PMID22273163
OpenAlexW2094412861
LanguageEN
Citations received1
References cited12

This paper suggests that the P2 allele of the P blood group system serves as an adaptation to a hypothesized Generalized Helminthic Antigenic Complex shared by many helminthic zoonoses. Since helminthic zoonoses are largely dependent on subsistence practices requiring animal contact, higher P2 frequencies should be observed where there is heavy dependence on such practices. Subsistence data and P2 gene frequencies for 187 groups are analyzed. Significant correlations between degree of dependence on animal-oriented subsistence practices and P2 frequencies support the hypothesis. Studies of this type may demonstrate the links between culture, infectious diseases, and genetic traits

Adaptation (eye · Biology · Evolutionary biology · Group (periodic table · Helminths · Zoology · Chemistry · Parasite Biology and Host Interactions

  • The Anthropology of Infectious Disease

    M C Inhorn, Peter J Brown•Annual Review of Anthropology•1990

  • Population structure and human variation

    G A Harrison•Population structure and human…•1977

  • The American Journal of Human Genetics

    Open Access•J S•Population•1950

Citations per year0.03
Citation span1990 - 1990 (1)
Highly citedNo

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