Why continuing uncertainties are no reason to postpone challenge trials for coronavirus vaccines
Bibliographic Data
| ID | 21515055 |
|---|---|
| Authors | Robert Steel (0000-0003-4879-2070, Rutgers, the State University of New Jersey), Lara Buchak (0000-0002-0232-4274, Princeton University), Nir Eyal (0000-0003-1056-6609, Rutgers, the State University of New Jersey, corresponding author) |
| Year | 2020 |
| Volume | 46 |
| Issue | 12 |
| Pages | 808-812 |
| Publication date | 2020-12-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Medical Ethics (JOURNAL) |
| Journal identifiers | ISSN: 0306-6800 • E-ISSN: 1473-4257 |
| Publisher | BMJ (PUBLISHER • GB) |
| DOI | 10.1136/medethics-2020-106501 |
| PMID | 32661074 |
| OpenAlex | W3041915940 |
| Language | EN |
| Citations received | 7 |
| References cited | 24 |
To counter the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), some have proposed accelerating SARS-CoV-2 vaccine development through controlled human infection (or ‘challenge’) trials. These trials would involve the deliberate exposure of relatively few young, healthy volunteers to SARS-CoV-2. We defend this proposal against the charge that there is still too much uncertainty surrounding the risks of COVID-19 to responsibly run such a trial
2019-20 coronavirus outbreak · Betacoronavirus · Coronavirus · Coronavirus Infections · Data science · MEDLINE · Outbreak · Pandemic · Pathology · Political science · Computer Science · Law · Medicine · SARS-CoV-2 and COVID-19 Research · Vaccine Coverage and Hesitancy · Viral Infections and Outbreaks Research · Virology
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A Core Precautionary Principle
| Citations per year | 1.17 |
|---|---|
| Citation span | 2020 - 2026 (7) |
| Highly cited | No |